RNA-Seq: a revolutionary tool for transcriptomics
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TLDR
The RNA-Seq approach to transcriptome profiling that uses deep-sequencing technologies provides a far more precise measurement of levels of transcripts and their isoforms than other methods.Abstract:
RNA-Seq is a recently developed approach to transcriptome profiling that uses deep-sequencing technologies. Studies using this method have already altered our view of the extent and complexity of eukaryotic transcriptomes. RNA-Seq also provides a far more precise measurement of levels of transcripts and their isoforms than other methods. This article describes the RNA-Seq approach, the challenges associated with its application, and the advances made so far in characterizing several eukaryote transcriptomes.read more
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Type 2 innate lymphoid cells disrupt bronchial epithelial barrier integrity by targeting tight junctions through IL-13 in asthmatic patients.
Kazunari Sugita,Kazunari Sugita,Catherine A. Steer,Itziar Martinez-Gonzalez,Can Altunbulakli,Hideaki Morita,Francesc Castro-Giner,Francesc Castro-Giner,Terufumi Kubo,Paulina Wawrzyniak,Beate Rückert,Katsuko Sudo,Susumu Nakae,Susumu Nakae,Kenji Matsumoto,Liam O'Mahony,Mübeccel Akdis,Fumio Takei,Cezmi A. Akdis +18 more
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IsoLasso: a LASSO regression approach to RNA-Seq based transcriptome assembly.
Wei Li,Jianxing Feng,Tao Jiang +2 more
TL;DR: IsoLasso is a new RNA-Seq based transcriptome assembly tool based on the well-known LASSO algorithm, a multivariate regression method designated to seek a balance between the maximization of prediction accuracy and the minimization of interpretation.
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Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development
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Genome-wide Transcriptional Profiling of Appressorium Development by the Rice Blast Fungus Magnaporthe oryzae
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Systems Biology in Immunology: A Computational Modeling Perspective ∗
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