Journal ArticleDOI
Role of catecholamines in stimulating the release of pituitary ovulating hormone(s) in rats.
Reads0
Chats0
TLDR
Infusions into the third ventricle indicated that CA act as neural triggers... and that changes in the dynamics of depletion of hypothalamic catecholamines (CA) may affect the stimulation of ovulation.Abstract:
This study tests the hypothesis that changes in the dynamics of depletion of hypothalamic catecholamines (CA) may affect the stimulation of ovulation. Partial as well as total depletions of CA were attempted by appropriately timed injections of reserpine and inhibitors of monoamine-oxidase. Treatment with reserpine in the morning of proestrus inhibited spontaneous ovulation and elevated the electrical threshold of the medial preoptic area but did not alter the threshold for inducing ovulation by stimulating the median eminencearcuate nucleus region. At high levels of current both areas responded similarly with stimulation of ovulation. Complete blockade of the electrically stimulated release of ovulating hormone was obtained 18–20 hr after treatment with reserpine. However, even after this prolonged reserpine action inhibitors of monoamine-oxidase restored enough CA to support electrically stimulated but not spontaneous ovulation. Infusions into the third ventricle indicated that CA act as neural triggers...read more
Citations
More filters
Journal ArticleDOI
Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain
TL;DR: The hypothesis is given that the PNMT containing neurons represent A containing neurons, and that A may act as a neurotransmitter in the rat brain.
Book ChapterDOI
CHAPTER 43 – Neuroendocrine Control of the Ovarian Cycle of the Rat
TL;DR: In this paper, the authors discuss the control of the ovarian cycle of the rats by the brain and its interaction with the anterior pituitary gland and ovaries and show that lighting periodicity plays a dominant role in the incidence and duration of the stages of the cycle.
Journal ArticleDOI
Catecholaminergic modulation of luteinizing hormone-releasing hormone release by median eminence terminals in vitro.
TL;DR: Release of radioimmunoassayable LHRH from hypothalamic fragments of adult male rats was measured using an in vitro incubation system and increased release from the ME, was 10 to 15-fold higher than that from the MBH or theMBH-ME unit.
Journal ArticleDOI
Gonadal steroid action on the brain: neurochemistry and neuropharmacology.
Bruce S. McEwen,Bruce Parsons +1 more
TL;DR: Studies of the action of steroid honnones on the brain have progressed to a point where specific mechanisms and brain sites of action are now recognized, and especially important to the neurophannacologist are aspects of mechanism which have begun to deal with hormonal modifica tion of properties and functions of synapses.
Journal ArticleDOI
3H estradiol in catecholamine neurons of rat brain stem: Combined localization by autoradiography and formaldehyde-induced fluorescence
Lester D. Grant,Walter E. Stumpf +1 more
TL;DR: The estradiol‐CA neuron relationships described may provide morphological substrates underlying functional interactions between Estradiol and CA neurons in the rat brain and suggest a second mode of interaction between CA neurons and estrogen target neurons.