Rotors and the Dynamics of Cardiac Fibrillation
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...lation is a consequence of the continued activity of a few vortices (rotors) that spin at high frequencies, generating ‘fibrillatory conduction’ [236,237]....
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...In simulations, they used a 2D sheet of ventricular cells incorporating the 1991 kinetics of Luo and Rudy.(47) For experiments, they used a thin slice of sheep ventricular epicardium; the slice was perfused with a voltage-sensitive dye and optically mapped....
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...In simulations, they used a 2D sheet of ventricular cells incorporating the 1991 kinetics of Luo and Rudy.47 For experiments, they used a thin slice of sheep ventricular epicardium; the slice was perfused with a voltage-sensitive dye and optically mapped.46 An artificial linear obstacle was etched into the ventricular muscle sheet in both simulations and experiments (depicted in a cartoon in Figure 2B, where the obstacle is represented by a red line)....
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