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Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label, randomised controlled trial

Nathan J Brendish, +11 more
- 01 May 2017 - 
- Vol. 5, Iss: 5, pp 401-411
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TLDR
Routine use of molecular POCT for respiratory viruses did not reduce the proportion of patients treated with antibiotics, and POCT was not associated with a reduction in the duration of antibiotics overall.
About: 
This article is published in The Lancet Respiratory Medicine.The article was published on 2017-05-01 and is currently open access. It has received 196 citations till now. The article focuses on the topics: Emergency department.

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Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa

Timothy M. Uyeki, +19 more
- 05 Mar 2019 - 
TL;DR: These clinical practice guidelines are an update of the guidelines published by the Infectious Diseases Society of America in 2009 and address new information regarding diagnostic testing, treatment and chemoprophylaxis with antiviral medications, and issues related to institutional outbreak management for seasonal influenza.
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Syndromic Panel-Based Testing in Clinical Microbiology

Poornima Ramanan, +4 more
- 15 Nov 2017 - 
TL;DR: This review focuses on U.S. Food and Drug Administration-approved/cleared multiplex molecular panels with more than five targets designed to assist in the diagnosis of bloodstream, respiratory tract, gastrointestinal, or central nervous system infections.
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Saliva as a diagnostic specimen for testing respiratory virus by a point-of-care molecular assay: a diagnostic validity study.

Kelvin K. W. To, +17 more
- 01 Mar 2019 - 
TL;DR: Saliva specimens have high sensitivity and specificity in the detection of respiratory viruses by an automated multiplex Clinical Laboratory Improvement Amendments-waived point-of-care molecular assay when compared with those of NPA.
Journal ArticleDOI

Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study.

Nathan J Brendish, +15 more
- 01 Dec 2020 - 
TL;DR: Point-of-care testing is associated with large reductions in time to results and could lead to improvements in infection control measures and patient flow compared with centralised laboratory PCR testing.
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Evaluation of the QIAstat-Dx Respiratory SARS-CoV-2 Panel, the First Rapid Multiplex PCR Commercial Assay for SARS-CoV-2 Detection.

Benoit Visseaux, +14 more
- 23 Jul 2020 - 
TL;DR: The QIAstat-SARS rapid multiplex PCR panel provides a highly sensitive, robust, and accurate assay for rapid detection of SARS-CoV-2, which allows rapid decisions even in non-PCR-trained laboratory or point-of-care testing, allowing innovative organization.
References
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Journal ArticleDOI

Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohsen Naghavi, +731 more
- 10 Jan 2015 - 
TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as discussed by the authors, the authors used the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.
Journal ArticleDOI

Community-acquired pneumonia requiring hospitalization among U.S. adults

Seema Jain, +31 more
- 29 Jul 2015 - 
TL;DR: The incidence of community-acquired pneumonia requiring hospitalization was highest among the oldest adults and despite current diagnostic tests, no pathogen was detected in the majority of patients.
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Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.

Stella G. Muthuri, +87 more
- 01 May 2014 - 
TL;DR: There was an increase in the mortality hazard rate with each day's delay in initiation of treatment up to day 5 as compared with treatment initiated within 2 days of symptom onset, and early treatment versus no treatment was also associated with a reduction in mortality risk.

Chronic obstructive pulmonary disease: Management of chronic obstructive pulmonary disease in adults in primary and secondary care

Melvyn Jones
TL;DR: Management of chronic obstructive pulmonary disease in adults in primary and secondary care (partial update)
Journal ArticleDOI

Accuracy of rapid influenza diagnostic tests: a meta-analysis.

Caroline Chartrand, +4 more
- 03 Apr 2012 - 
TL;DR: In this article, the authors examined the accuracy of rapid influenza diagnostic tests (RIDTs) in adults and children with influenza-like illness and evaluated factors associated with higher accuracy.
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