Journal ArticleDOI
Seasonal immune function and sickness responses.
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TLDR
It is proposed that photoperiodic information, mediated by melatonin, might also influence immune responses, and enhance immune function and increased survival in animals during winter.About:
This article is published in Trends in Immunology.The article was published on 2004-04-01. It has received 302 citations till now.read more
Citations
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Journal ArticleDOI
Carcinogenicity of shift-work, painting, and fire-fighting.
Kurt Straif,Robert Baan,Yann Grosse,Béatrice Secretan,Fatiha El Ghissassi,Véronique Bouvard,Andrea Altieri,Lamia Benbrahim-Tallaa,Vincent Cogliano +8 more
TL;DR: The Working Group concluded that “shift-work that involves circadian disruption is probably carcinogenic to humans” (Group 2A).
Journal ArticleDOI
A review of the multiple actions of melatonin on the immune system
TL;DR: The presence of immune system-synthesized melatonin, its direct immunomodulatory effects on cytokine production, and its masking effects on exogenous melatonin action are summarized.
Journal ArticleDOI
Linking immune defenses and life history at the levels of the individual and the species.
TL;DR: A framework integrating immunological and life history axes is created that predicts that "fast-living" species should rely more heavily on nonspecific and inflammatory immune defenses, while "slow-living%" species should exhibit stronger specific and especially antibody-mediated immunity.
Journal ArticleDOI
Seasonal changes in vertebrate immune activity: mediation by physiological trade-offs
TL;DR: Evidence supporting the hypothesis that physiological trade-offs, particularly those between the reproductive and immune systems, mediate part of the seasonal changes detected in the immune defences of many vertebrates is reviewed.
Journal ArticleDOI
Cytokine, Sickness Behavior, and Depression
TL;DR: Sufficient evidence is now available to accept the concept that the brain recognizes cytokines as molecular signals of sickness, and a dynamic view of the cellular interactions that occur at the brain sites of cytokine production and action is missing.
References
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Journal ArticleDOI
The evolution of life histories
TL;DR: In this article, age and size at maturity at maturity number and size of offspring Reproductive lifespan and ageing are discussed. But the authors focus on the effects of age and stage structure on fertility.
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Ecological immunology: costly parasite defences and trade-offs in evolutionary ecology
Ben C. Sheldon,Simon Verhulst +1 more
TL;DR: Viewing an individual's immune response to parasites as being subject to optimization in the face of other demands offers potential insights into mechanisms of life history trade-offs, sexual selection, parasite-mediated selection and population dynamics.
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Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.
Yi Guan,Bo-Jian Zheng,Yuxian He,X. L. Liu,Z. X. Zhuang,CL Cheung,S. W. Luo,Philip H. Li,L. J. Zhang,Y. J. Guan,K. M. Butt,K. L. Wong,K. W. Chan,Wilina Lim,Kennedy F. Shortridge,K. Y. Yuen,Joseph S. M. Peiris,Leo L.M. Poon +17 more
TL;DR: The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.
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Biological basis of the behavior of sick animals
TL;DR: Findings from recent lines of research are reviewed to formulate the perspective that the behavior of sick animals and people is not a maladaptive response or the effect of debilitation, but rather an organized, evolved behavioral strategy to facilitate the role of fever in combating viral and bacterial infections.
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Trade‐offs in evolutionary immunology: just what is the cost of immunity?
TL;DR: It is concluded that sufficient evidence exists to support the primary assumption that immunological defences are costly to the vertebrate host and how costly it might be for a host who is forced to up-regulate its immunological defence mechanisms.