Self-reported smell and taste recovery in coronavirus disease 2019 patients: a one-year prospective study.
Paolo Boscolo-Rizzo,Francesco Guida,Jerry Polesel,Alberto Vito Marcuzzo,Paolo Antonucci,Vincenzo Capriotti,Erica Sacchet,Fiordaliso Cragnolini,Andrea D'Alessandro,Enrico Zanelli,Riccardo Marzolino,Chiara Lazzarin,Margherita Tofanelli,Nicoletta Gardenal,Daniele Borsetto,Claire Hopkins,Luigi Angelo Vaira,Giancarlo Tirelli +17 more
Reads0
Chats0
TLDR
A substantial proportion of patients with previous mild-to-moderate symptomatic COVID-19 characterized by new onset of chemosensory dysfunction still complained on altered sense of smell or taste 1 year after the onset.Citations
More filters
Journal ArticleDOI
Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia
Marianna Zazhytska,Albana Kodra,Daisy A. Hoagland,Justin J. Frere,John F. Fullard,Hani J. Shayya,Natalie McArthur,Rasmus Moeller,Skyler Uhl,Arina D. Omer,Max E. Gottesman,Stuart Firestein,Qizhi Gong,Peter Canoll,James E. Goldman,Panos Roussos,Benjamin R. tenOever,Jonathan B. Overdevest,Stavros Lomvardas +18 more
TL;DR: In this paper , the authors show that SARS-CoV-2 infection causes widespread downregulation of olfactory receptors (ORs) and of their signaling components, followed by a dramatic reorganization of the neuronal nuclear architecture, which results in dissipation of genomic compartments harboring OR genes.
Journal ArticleDOI
Symptoms and Health Outcomes Among Survivors of COVID-19 Infection 1 Year After Discharge From Hospitals in Wuhan, China.
Xue Zhang,Fang Wang,Ye Shen,Xiaohua Zhang,Yuan Cen,Bin Wang,Songtao Zhao,Yi Zhou,Baoman Hu,Man Wang,Yu-Hui Liu,Hongming Miao,Paul W. Jones,Xiangyu Ma,Yong He,Guoqiang Cao,Lixia Cheng,Li Li +17 more
TL;DR: Wang et al. as mentioned in this paper evaluated health outcomes of COVID-19 survivors 1 year after hospital discharge and identified associated risk factors, including fatigue, sweating, chest tightness, anxiety, and myalgia.
Journal ArticleDOI
Prognosis and persistence of smell and taste dysfunction in patients with covid-19: meta-analysis with parametric cure modelling of recovery curves
Benjamin K.J. Tan,Ruobing Han,Joseph J. Zhao,N. C. K. Tan,Emrick Sen Hui Quah,C. Tan,Yiong Huak Chan,Neville Wei Yang Teo,Tze Choong Charn,Anna See,Shuhui Xu,Nikita Chapurin,Ramesh Chandra,Naweed I. Chowdhury,Rafal Butowt,Christopher S. von Bartheld,B. Nirmal Kumar,Claire Hopkins,Song Tar Toh +18 more
TL;DR: In this paper , a systematic review and meta-analysis was performed to explore unadjusted associations of prognostic factors associated with recovery of smell and taste in patients with covid-19.
Journal ArticleDOI
Coronavirus disease 2019 (COVID‐19)–related smell and taste impairment with widespread diffusion of severe acute respiratory syndrome–coronavirus‐2 (SARS‐CoV‐2) Omicron variant
Paolo Boscolo-Rizzo,Giancarlo Tirelli,Pierluigi Meloni,Claire Hopkins,Giordano Madeddu,Andrea De Vito,Nicoletta Gardenal,Romina Valentinotti,Margherita Tofanelli,Daniele Borsetto,Jerome R. Lechien,Jerry Polesel,Giacomo De Riu,Luigi Angelo Vaira +13 more
TL;DR: The aim of this study was to estimate the prevalence of self‐reported chemosensory dysfunction in a study cohort of subjects who developed a mild‐to‐moderate coronavirus disease 2019 and compared that with a historical series of patients testing positive for severe acute respiratory syndrome–coronavirus‐2 (SARS‐CoV‐2) infection between March and April, 2020.
Journal ArticleDOI
The Effects of Persistent Olfactory and Gustatory Dysfunctions on Quality of Life in Long-COVID-19 Patients
Luigi Angelo Vaira,Claudia Gessa,Giovanna Deiana,Giovanni Salzano,Fabio Maglitto,Jerome R. Lechien,Sven Saussez,Pasquale Piombino,Andrea Biglio,Federico Biglioli,Paolo Boscolo-Rizzo,Claire Hopkins,Valentina Parma,Giacomo De Riu +13 more
TL;DR: POD and PGD are frequent symptoms of the long-COVID-19 syndrome and significantly reduce QoL, specifically in the mental health component, and should stimulate the establishment of appropriate infrastructure to support individuals with persistent CD.
References
More filters
Journal ArticleDOI
Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study.
Jerome R. Lechien,Carlos M. Chiesa-Estomba,Daniele R De Siati,Mihaela Horoi,Serge D Le Bon,Alexandra Rodriguez,Didier Dequanter,Serge Blecic,Fahd El Afia,Lea Distinguin,Younes Chekkoury-Idrissi,Stéphane Hans,Irene Lopez Delgado,Christian Calvo-Henriquez,Philippe Lavigne,Chiara Falanga,Maria Rosaria Barillari,Giovanni Cammaroto,Mohamad Khalife,Pierre Leich,Christel Souchay,Camelia Rossi,Fabrice Journe,Julien Hsieh,Myriam Edjlali,Myriam Edjlali,Robert Carlier,Laurence Ris,Andrea Lovato,Cosimo de Filippis,Frédérique Coppée,Nicolas Fakhry,Tareck Ayad,Sven Saussez +33 more
TL;DR: Olfactory and gustatory disorders are prevalent symptoms in European CO VID-19 patients, who may not have nasal symptoms, and the sudden anosmia or ageusia need to be recognized by the international scientific community as important symptoms of the COVID-19 infection.
Journal ArticleDOI
Psychometric validity of the 22-item Sinonasal Outcome Test.
TL;DR: The psychometric validation of a disease‐specific health related quality of life instrument for use in chronic rhinosinusitis is determined, the 22 item Sinonasal Outcome Test (SNOT‐22), a modification of a pre‐existing instrument, the SNOT‐20.
Journal ArticleDOI
Prevalence of olfactory impairment in older adults.
Claire Murphy,Carla R. Schubert,Karen J. Cruickshanks,Barbara E.K. Klein,Ronald Klein,David M. Nondahl +5 more
TL;DR: It is demonstrated that prevalence of olfactory impairment among older adults is high and increases with age, and self-report significantly underestimated prevalence rates obtained by olfaction testing.
Journal ArticleDOI
Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center.
Daniel A. Deems,Richard L. Doty,R.G. Settle,V Moore-Gillon,Paul Shaman,A. Mester,CP Kimmelman,VJ Brightman,Jr Jb Snow +8 more
TL;DR: A study of 750 patients with complaints of abnormal smell or taste perception from the University of Pennsylvania Smell and Taste Center, Philadelphia suggests that chemosensory dysfunction influences quality of life.
Journal ArticleDOI
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia.
David H. Brann,Tatsuya Tsukahara,Caleb Weinreb,Marcela Lipovsek,Koen Van den Berge,Koen Van den Berge,Boying Gong,Rebecca K. Chance,Iain C. Macaulay,Hsin-jung Chou,Russell B. Fletcher,Diya Das,Diya Das,Kelly Street,Hector Roux de Bézieux,Yoon Gi Choi,Davide Risso,Sandrine Dudoit,Elizabeth Purdom,Jonathan Mill,Ralph Abi Hachem,Hiroaki Matsunami,Darren W. Logan,Bradley J. Goldstein,Matthew S. Grubb,John Ngai,Sandeep Robert Datta +26 more
TL;DR: It is suggested that CoV-2 infection of non-neuronal cell types leads to anosmia and related disturbances in odor perception in COVID-19 patients.
Related Papers (5)
Evolution of Altered Sense of Smell or Taste in Patients With Mildly Symptomatic COVID-19.
Paolo Boscolo-Rizzo,Daniele Borsetto,Cristoforo Fabbris,Giacomo Spinato,Daniele Frezza,Anna Menegaldo,Francesca Mularoni,Piergiorgio Gaudioso,Diego Cazzador,Silvia Marciani,Samuele Frasconi,Maria Ferraro,Cecilia Berro,Chiara Varago,Piero Nicolai,Giancarlo Tirelli,Maria Cristina Da Mosto,Rupert Obholzer,Roberto Rigoli,Jerry Polesel,Claire Hopkins +20 more