Sensitivity advantage of swept source and Fourier domain optical coherence tomography
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TLDR
Results are presented which demonstrate the superior sensitivity of swept source (SS) and Fourier domain (FD) optical coherence tomography (OCT) techniques over the conventional time domain (TD) approach.Abstract:
We present theoretical and experimental results which demonstrate the superior sensitivity of swept source (SS) and Fourier domain (FD) optical coherence tomography (OCT) techniques over the conventional time domain (TD) approach. We show that SS- and FD-OCT have equivalent expressions for system signal-to-noise ratio which result in a typical sensitivity advantage of 20-30dB over TD-OCT. Experimental verification is provided using two novel spectral discrimination (SD) OCT systems: a differential fiber-based 800nm FD-OCT system which employs deep-well photodiode arrays, and a differential 1300nm SS-OCT system based on a swept laser with an 87nm tuning range.read more
Citations
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Journal ArticleDOI
Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
Yali Jia,Ou Tan,Jason Tokayer,Benjamin Potsaid,Y. Wang,Jonathan J. Liu,Martin F. Kraus,Hrebesh M. Subhash,James G. Fujimoto,Joachim Hornegger,David Huang +10 more
TL;DR: In this paper, a split-spectrum amplitude-decorrelation angiography (SSADA) was proposed to improve the signal-to-noise ratio (SNR) of flow detection.
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Measurement of intraocular distances by backscattering spectral interferometry
TL;DR: In this article, the diffraction tomography theorem is adapted to one-dimensional length measurement and the resulting spectral interferometry technique is described and the first length measurements using this technique on a model eye and on a human eye in vivo are presented.
Journal ArticleDOI
Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation.
Maciej Wojtkowski,Vivek J. Srinivasan,Tony H. Ko,James G. Fujimoto,Andrzej Kowalczyk,Jay S. Duker +5 more
TL;DR: High-resolution spectral domain OCT is shown to provide a ~100x increase in imaging speed when compared to ultrahigh-resolution time domain OCT, and a general technique for automatic numerical dispersion compensation is presented, which is applicable to spectral domain as well as swept source embodiments of Fourier domain OCT.
Journal Article
Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
Yali Jia,Ou Tan,Jason Tokayer,Benjamin Potsaid,Y. Wang,Jonathan J. Liu,Martin F. Kraus,Hrebesh M. Subhash,James G. Fujimoto,Joachim Hornegger,David Huang +10 more
TL;DR: In this paper, a split-spectrum amplitude-decorrelation angiography (SSADA) was proposed to improve the signal-to-noise ratio (SNR) of flow detection.
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Retinal Imaging and Image Analysis
TL;DR: Methods for 2-D fundus imaging and techniques for 3-D optical coherence tomography (OCT) imaging are reviewed and aspects of image acquisition, image analysis, and clinical relevance are treated together considering their mutually interlinked relationships.
References
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Journal ArticleDOI
Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TL;DR: OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.
Book ChapterDOI
Optical Coherence Tomography
Eric A. Swanson,J. Izatt,M. Bee,David Huang,Charles P. Lin,Carmen A. Puliafito,Carmen A. Puliafito,James G. Fujimoto +7 more
TL;DR: Optical coherence tomography (OCT) has developed rapidly since its first realisation in medicine and is currently an emerging technology in the diagnosis of skin disease as mentioned in this paper, where OCT is an interferometric technique that detects reflected and backscattered light from tissue.
Journal ArticleDOI
Performance of fourier domain vs. time domain optical coherence tomography.
TL;DR: It is shown that FDOCT systems have a large sensitivity advantage and allow for sensitivities well above 80dB, even in situations with low light levels and high speed detection.
Journal Article
Measurement of intraocular distances by backscattering spectral interferometry
TL;DR: In this article, the diffraction tomography theorem is adapted to one-dimensional length measurement and the resulting spectral interferometry technique is described and the first length measurements using this technique on a model eye and on a human eye in vivo are presented.
Journal ArticleDOI
Measurement of intraocular distances by backscattering spectral interferometry
TL;DR: In this paper, the diffraction tomography theorem is adapted to one-dimensional length measurement and the resulting spectral interferometry technique is described and the first length measurements using this technique on a model eye and on a human eye in vivo are presented.