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Journal ArticleDOI

Simultaneous and Accurate Quantification of Multiple Antibiotics in Aquatic Samples by Surface-Enhanced Raman Scattering Using a Ti3C2Tx/DNA/Ag Membrane Substrate.

13 Sep 2021-Analytical Chemistry (American Chemical Society (ACS))-Vol. 93, Iss: 38, pp 13072-13079
TL;DR: In this article, the authors developed a rapid and accurate strategy for simultaneous quantification of trace multiple antibiotic residues in complex aquatic samples by surface-enhanced Raman scattering (SERS) using a Ti3C2Tx/DNA/Ag membrane substrate.
Abstract: Rapid and accurate analysis of multiple targets in complex samples is still a big challenge in the fast detection field. Herein, we developed a rapid and accurate strategy for simultaneous quantification of trace multiple antibiotic residues in complex aquatic samples by surface-enhanced Raman scattering (SERS) using a Ti3C2Tx/DNA/Ag membrane substrate. This membrane substrate was proven to have good uniformity, reproducibility, stability, and SERS activity by a series of characterizations. Also, this substrate combined excellent electromagnetic enhancement and chemical enhancement effects, which endowed it with good sensitivity and selectivity during SERS analysis. It achieved the integration of multitarget separation, enrichment, and in situ detection, which significantly improved the selectivity, sensitivity, accuracy, and detection throughput by membrane substrate coupling with SERS for real-sample analysis. Finally, this rapid SERS analysis strategy was successfully applied to the simultaneous quantification of trace nitrofurantoin (NFT) and ofloxacin (OFX) in aquatic samples. It was observed that trace NFT and OFX were actually detected and simultaneously quantified to be 8.0-13.7 and 42.6-49.1 μg/kg in aquatic samples, respectively, with good recoveries of 88.0-107% and relative standard deviations of 0.3-5.5%. The results were verified by a traditional high-performance liquid chromatography method with relative errors of -9.8 to 5.3%. This strategy provided a methodological reference for accurate SERS quantification of multiple targets in complex samples.
Citations
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Journal ArticleDOI
TL;DR: In this paper , a review of sample preparation techniques for surface-enhanced Raman spectroscopy (SERS) analysis of complex matrices is presented, where the authors present a "all-in-one" strategy for simultaneous separation, enrichment, and in-situ SERS detection.

9 citations

Journal ArticleDOI
TL;DR: In this paper , a branched Au-alloy doped mesoporous graphitic carbon nitride hybrid membrane (mpg-C3N4/AuCu) was fabricated for SERS analysis of carcinogens including benzidine and zearalenone in food.

9 citations

Journal ArticleDOI
TL;DR: In this paper , the authors comprehensively review the recent advances made in the field of solid SERS substrates, including their common fabrication methods, basic categories, main features, and representative applications, respectively.

3 citations

Journal ArticleDOI
TL;DR: In this paper , Ag nanoparticles decorated MOF-74 (Ni) encapsulated magnetic prickly-like nickel rods were firstly designed and fabricated for simultaneous surface-enhanced Raman spectroscopy (SERS) analysis of mycotoxins in food samples.
Abstract: Herein, Ag nanoparticles decorated MOF-74 (Ni) encapsulated magnetic prickly-like nickel rods ([email protected] (Ni)/Ag) was firstly designed and fabricated for simultaneous surface-enhanced Raman spectroscopy (SERS) analysis of mycotoxins in food samples. The prickly-like NiRs not only provide magnetism with anisotropy structure, but also directly supply Ni2+ for surface initiated encapsulation of MOF-74 (Ni) on NiRs. The as-fabricated [email protected] (Ni)/Ag exhibits good SERS activity due to the enrichment effect of magnetic NiRs, adsorption of MOF-74 (Ni) and localized surface plasmon resonance properties of AgNPs. The enhancement factor for 5,5′-dithiobis-(2-nitrobenzoic acid) and 4-mercaptobenzoic acid can reach 108 level with limits of detection (LOD) of 1.0 ng/L. Subsequently, the magnetic aptamer probes based on [email protected] (Ni)/Ag were fabricated for simultaneous, sensitive and selective SERS analysis of T-2 and deoxynivalenol in food samples. The method exhibited satisfactory linearity in range of 0.5–750.0 μg/L and 0.3–750.0 μg/L with LOD of 0.15 and 0.08 μg/L for T-2 and deoxynivalenol, respectively. The relative errors between the developed method and standard HPLC-MS ranged from −7.7 to 1.4%. Our results open a new venue in design and fabrication of magnetic SERS substrates with unique property for quantification of multiple mycotoxins in complex samples.

3 citations

References
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Journal ArticleDOI
TL;DR: In this article, a new family of two-dimensional early transition metal carbides and carbonitrides, called MXenes, was discovered and a detailed outlook for future research on MXenes is also presented.
Abstract: Recently a new, large family of two-dimensional (2D) early transition metal carbides and carbonitrides, called MXenes, was discovered. MXenes are produced by selective etching of the A element from the MAX phases, which are metallically conductive, layered solids connected by strong metallic, ionic, and covalent bonds, such as Ti2AlC, Ti3AlC2, and Ta4AlC3. MXenes ­combine the metallic conductivity of transition metal carbides with the hydrophilic nature of their hydroxyl or oxygen terminated surfaces. In essence, they behave as “conductive clays”. This article reviews progress—both ­experimental and theoretical—on their synthesis, structure, properties, intercalation, delamination, and potential applications. MXenes are expected to be good candidates for a host of applications. They have already shown promising performance in electrochemical energy storage systems. A detailed outlook for future research on MXenes is also presented.

3,973 citations

Journal ArticleDOI
13 Feb 2012-ACS Nano
TL;DR: Evidence is presented for the exfoliation of the following MAX phases by the simple immersion of their powders, at room temperature, in HF of varying concentrations for times varying between 10 and 72 h followed by sonication.
Abstract: Herein we report on the synthesis of two-dimensional transition metal carbides and carbonitrides by immersing select MAX phase powders in hydrofluoric acid, HF. The MAX phases represent a large (>60 members) family of ternary, layered, machinable transition metal carbides, nitrides, and carbonitrides. Herein we present evidence for the exfoliation of the following MAX phases: Ti2AlC, Ta4AlC3, (Ti0.5,Nb0.5)2AlC, (V0.5,Cr0.5)3AlC2, and Ti3AlCN by the simple immersion of their powders, at room temperature, in HF of varying concentrations for times varying between 10 and 72 h followed by sonication. The removal of the “A” group layer from the MAX phases results in 2-D layers that we are labeling MXenes to denote the loss of the A element and emphasize their structural similarities with graphene. The sheet resistances of the MXenes were found to be comparable to multilayer graphene. Contact angle measurements with water on pressed MXene surfaces showed hydrophilic behavior.

3,080 citations

Journal ArticleDOI
TL;DR: The ability to control the size, shape, and material of a surface has reinvigorated the field of surface-enhanced Raman spectroscopy (SERS) as mentioned in this paper.
Abstract: The ability to control the size, shape, and material of a surface has reinvigorated the field of surface-enhanced Raman spectroscopy (SERS). Because excitation of the localized surface plasmon resonance of a nanostructured surface or nanoparticle lies at the heart of SERS, the ability to reliably control the surface characteristics has taken SERS from an interesting surface phenomenon to a rapidly developing analytical tool. This article first explains many fundamental features of SERS and then describes the use of nanosphere lithography for the fabrication of highly reproducible and robust SERS substrates. In particular, we review metal film over nanosphere surfaces as excellent candidates for several experiments that were once impossible with more primitive SERS substrates (e.g., metal island films). The article also describes progress in applying SERS to the detection of chemical warfare agents and several biological molecules.

2,578 citations

Journal ArticleDOI
TL;DR: Two-dimensional transition metal carbides, carbonitrides, and nitrides (MXenes) were discovered in 2011 and more than 20 different compositions have been synthesized by the selective etching of MAX phase and other precursors and many more theoretically predicted as mentioned in this paper.
Abstract: Two-dimensional (2D) transition metal carbides, carbonitrides, and nitrides (MXenes) were discovered in 2011. Since the original discovery, more than 20 different compositions have been synthesized by the selective etching of MAX phase and other precursors and many more theoretically predicted. They offer a variety of different properties, making the family promising candidates in a wide range of applications, such as energy storage, electromagnetic interference shielding, water purification, electrocatalysis, and medicine. These solution-processable materials have the potential to be highly scalable, deposited by spin, spray, or dip coating, painted or printed, or fabricated in a variety of ways. Due to this promise, the amount of research on MXenes has been increasing, and methods of synthesis and processing are expanding quickly. The fast evolution of the material can also be noticed in the wide range of synthesis and processing protocols that determine the yield of delamination, as well as the quality...

2,559 citations

Journal ArticleDOI
TL;DR: In this article, the authors present an in-depth study of surface enhanced Raman scattering (SERS) enhancement factors and cross-sections, including several issues often overlooked, and demonstrate that SERS EFs as low as 107, as opposed to the figure of 1014 often claimed in the literature, are sufficient for SERS applications.
Abstract: This paper presents an in-depth study of Surface Enhanced Raman Scattering (SERS) enhancement factors (EFs) and cross-sections, including several issues often overlooked. In particular, various possible rigorous definitions of the SERS EFs are introduced and discussed in the context of SERS applications, such as analytical chemistry and single molecule SERS. These definitions highlight the importance of a careful characterization of the non-SERS cross-sections of the probes under consideration. This aspect is illustrated by experimental results for the non-SERS cross-sections of representative SERS probes along with average SERS EFs for the same probes. In addition, the accurate experimental determination of single molecule enhancement factors is tackled with two recently developed techniques, namely: bi-analyte SERS (BiASERS) and temperature-dependent SERS vibrational pumping. We demonstrate that SERS EFs as low as 107, as opposed to the figure of 1014 often claimed in the literature, are sufficient for...

2,298 citations