Simultaneous measurements of total pancreatic, biliary, and gastric outputs in man using a perfusion technique.
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The technique was used to show that total pancreatic enzyme output after intraduodenal stimulation by perfused amino acids was identical with that obtained after a maximally tolerated dose of pancreozymin given by vein, suggesting that conventional stimuli cannot attain maximal secretory capacity for enzymes.About:
This article is published in Gastroenterology.The article was published on 1970-03-01 and is currently open access. It has received 205 citations till now. The article focuses on the topics: Duodenum & Stomach.read more
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Relations between pancreatic enzyme outputs and malabsorption in severe pancreatic insufficiency.
TL;DR: To investigate the functioning reserve capacity of the exocrine pancreas, the relations of steatorrhea and creatorrhea to lipase and trypsin outputs in 17 patients with chronic pancreatic cancer are studied.
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Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man.
André Wettergren,Birgit Schjoldager,P. E. Mortensen,John Myhre,John Christiansen,Jens J. Holst +5 more
TL;DR: The results suggest that truncated GLP-1 act as a physiological inhibitor of gastric and pancreatic functions in man.
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Measurement of gastric functions during digestion of ordinary solid meals in man.
TL;DR: Using this method, acid, pepsin, and total secretory outputs; rates of gastric emptying of meal and secretions; and serum gastrin levels during digestion characterize physiological responses to ordinary food in health.
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Fate of orally ingested enzymes in pancreatic insufficiency. Comparison of two dosage schedules.
TL;DR: Prandial was as effective as hourly administration in decreasing steatorrhea and perhaps more effective in abolishing azotorrhea, and since it is also more convenient, it is recommend it.
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Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades.
Alan F. Hofmann,Lee R. Hagey +1 more
TL;DR: Bile acids are amphipathic, self-associate in solution, and form mixed micelles with polar lipids, phosphatidylcholine in bile, and fatty acids in intestinal content during triglyceride digestion.
References
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A turbidimetric method for the determination of higher polyethylene glycols in biological materials.
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A PHOTOMETRIC METHOD FOR THE DETERMINATION OF α-AMYLASE IN BLOOD AND URINE, WITH USE OF THE STARCH-IODINE COLOR
Benjamin W. Smith,Joseph H. Roe +1 more
TL;DR: A starch-iodine method for the determination of a-amylase in serum and urine in which the blue color formed by the reaction of starch with iodine is measured photometrically before and after incubation of soluble starch with material containing the enzyme.
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Absorption of Cholesterol from a Micellar Solution: Intestinal Perfusion Studies in Man*
TL;DR: The experiments confirm previous findings demonstrating that fat absorption without bile salt absorption occurs in the upper small intestine in man and suggest that polar lipid such as fatty acid or monoglyceride as well as bile Salt is essential for normal micellar solubilization of cholesterol in intestinal content.
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Distribution and fate of pancreatic enzymes in small intestine of the rat.
Daniel Pelot,Morton I. Grossman +1 more
TL;DR: Diversion of pancreatic juice to the exterior of the body resulted in rapid disappearance of enzymes from the small intestine with virtually complete absence after 16 hr.