Journal ArticleDOI
Sleep Disturbance in Acute Schizophrenic Patients
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TLDR
No definitive interpretation of these findings can yet be made; further extensive and systematic case studies are needed to determine whether the sleep disturbances reported here are an inherent aspect of all acute schizophrenic exacerbations.Abstract:
Sleep patterns were studied longitudinally in six acute schizophrenic patients throughout most of their hospital stays, ranging from 25 to 224 consecutive nights, and the data were compared with those from 15 normal control subjects. The sleep patterns of these six patients showed unique differences from those of the control subjects as well as from sleep patterns of severely depressed patients and normal subjects under experimental conditions. However, no definitive interpretation of these findings can yet be made; further extensive and systematic case studies are needed to determine whether the sleep disturbances reported here are an inherent aspect of all acute schizophrenic exacerbations.read more
Citations
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Sleep Disturbance as the Hallmark of Posttraumatic Stress Disorder
TL;DR: The results of neurophysiological studies in animals suggest that CNS processes generating REM sleep may participate in the control of the classical startle response, which may be akin to the startle behavior commonly described in PTSD patients.
Journal ArticleDOI
Is Schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited
TL;DR: Several lines of evidence support the notion that a substantial reorganization of cortical connections, involving a programmed synaptic pruning, takes place during adolescence in humans, and these models would have heuristic value and be consistent with several known facts of the schizophrenic illness.
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A Review of REM Sleep Deprivation
TL;DR: Controlled but unconfirmed work indicates that that endogenous, but not reactive, depressive patients are improved by REM sleep deprivation, a finding consistent with the animal behavioral consequences of the procedure and with the unique REM-depriving properties of efficacious antidepressant drugs.
Journal ArticleDOI
Interval between onset of sleep and rapid-eye-movement sleep as an indicator of depression
David J. Kupfer,F. Gordon Foster +1 more
TL;DR: An analysis of electroencephalographic patterns in thirty-five consecutive patients admitted for the treatment of depression revealed that a single sleep characteristic—the interval between onset of sleep and the start of rapid-eye-movement (R.E.M.M.) sleep—is an objective indicator of depressive disease and correlates inversely with its severity.
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Influence of sleep-wake and circadian rhythm disturbances in psychiatric disorders.
TL;DR: The results have implications for analyzing diurnal variation of mood in unipolar and bipolar affective disorders and sleep disturbances in other major psychiatric conditions such as chronic schizophrenia.
References
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Cyclic variations in EEG during sleep and their relation to eye movements, body motility, and dreaming.
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Dream recall and eye movements during sleep in schizophrenics and normals.
TL;DR: A memory recall and eye movement study during sleep in children with schizophrenia and adults with Alzheimer's disease are reported on.