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Journal ArticleDOI

Smart medical stocking using memory polymer for chronic venous disorders

01 Jan 2016-Biomaterials (Biomaterials)-Vol. 75, pp 174-181
TL;DR: This work aims to investigate and design a smart compression stocking using shape-memory polymer that allows externally controlling the pressure level in the wrapped position on the leg using external heat stimuli.
About: This article is published in Biomaterials.The article was published on 2016-01-01 and is currently open access. It has received 56 citations till now.

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Summary

  • Social inclusion, an essential element in the process of making friends, is recognised as a basic human right in the United Nations Convention on the Rights of Persons with Disabilities (United Nations General Assembly, 2006) in Article 19 on ‘Living independently and being included in the community’ and Article 30 on ‘Participation in cultural life, recreation, leisure and sport’.
  • For people with access to the internet and with online skills, this has enabled a wider group of social contacts beyond those typically limited by geographical boundaries.
  • Social exclusion and loneliness remain serious issues for people with a learning disability and much more needs to be done to realise their right to a full life in the community.
  • This article suggests that specific support should be targeted to overcome the barriers identified above that prevent people living full and safe lives in their communities.
  • Journal of Applied Research in Intellectual Disabilities, 17, 191-197.
  • In Community; Practical lessons in supporting isolated people to be part of community, Stockport: HSA Press.

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Citations
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Journal ArticleDOI
TL;DR: The blends containing 25% TPU and 75% PCL possessed the best shape memory properties as indicated by a 98% shape fixing ratio and 90% shape recovery ratio and it was found that PCL and TPU had good miscibility and that the PCL domain in TPU25% had higher crystallinity than neat PCL.
Abstract: Thermally responsive shape memory polymers have promising applications in many fields, especially in biomedical areas. In this study, a simple method was purposed to prepare thermoplastic polyurethane (TPU)/poly(e-caprolactone) (PCL) blends that possess shape memory attributes. TPU and PCL were melt compounded via a twin-screw extruder and injection molded at various ratios. Multiple test methods were used to characterize their shape memory properties and reveal the underling mechanism. The blends containing 25% TPU and 75% PCL possessed the best shape memory properties as indicated by a 98% shape fixing ratio and 90% shape recovery ratio. This was attributed to the hybrid crystalline and amorphous regions of PCL and TPU. We also found that PCL and TPU had good miscibility and that the PCL domain in TPU25% had higher crystallinity than neat PCL. The crystalline region in TPU25% could deform and maintain its temporary shape when stretched, which contributed to its high shape fixing attribute, while the rubbery TPU region assisted in the recovery of the sample upon heating by releasing the deformation energy stored. Moreover, the TPU25% string prepared could knot itself in a hot water bath, indicating a potential for suture applications. Lastly, the 3T3 fibroblast cells cultured on the TPU/PCL blends showed high viability and active substrate-cell interactions.

122 citations

Journal ArticleDOI
TL;DR: This original work is expected to provide inspiration for exploring other natural materials to reveal their smart functions and natural laws in animals including human as well as making more remarkable synthetic smart materials.
Abstract: Animal hairs consisting of α-keratin biopolymers existing broadly in nature may be responsive to water for recovery to the innate shape from their fixed deformation, thus possess smart behavior, namely shape memory effect (SME). In this article, three typical animal hair fibers were first time investigated for their water-stimulated SME, and therefrom to identify the corresponding net-points and switches in their molecular and morphological structures. Experimentally, the SME manifested a good stability of high shape fixation ratio and reasonable recovery rate after many cycles of deformation programming under water stimulation. The effects of hydration on hair lateral size, recovery kinetics, dynamic mechanical behaviors and structural components (crystal, disulfide and hydrogen bonds) were then systematically studied. SME mechanisms were explored based on the variations of structural components in molecular assemblies of such smart fibers. A hybrid structural network model with single-switch and twin-net-points was thereafter proposed to interpret the water-stimulated shape memory mechanism of animal hairs. This original work is expected to provide inspiration for exploring other natural materials to reveal their smart functions and natural laws in animals including human as well as making more remarkable synthetic smart materials.

59 citations

Journal ArticleDOI
TL;DR: The 30%PU/PCL polymer has the best shape-memory characteristics and can be knotted by itself in the hot water bath, indicating that it can be applied in smart suture applications and high biocompatibility due to high adhesion and proliferation.

58 citations

Journal ArticleDOI
21 Aug 2017-Sensors
TL;DR: This research investigated the sensing performance of five low-cost commercial pressure sensors on a human-leg-like test apparatus and presents quantitative results on the accuracy and drift behaviour of these sensors in both static and dynamic conditions required for compression therapy.
Abstract: The recent use of graduated compression therapy for treatment of chronic venous disorders such as leg ulcers and oedema has led to considerable research interest in flexible and low-cost force sensors. Properly applied low pressure during compression therapy can substantially improve the treatment of chronic venous disorders. However, achievement of the recommended low pressure levels and its accurate determination in real-life conditions is still a challenge. Several thin and flexible force sensors, which can also function as pressure sensors, are commercially available, but their real-life sensing performance has not been evaluated. Moreover, no researchers have reported information on sensor performance during static and dynamic loading within the realistic test conditions required for compression therapy. This research investigated the sensing performance of five low-cost commercial pressure sensors on a human-leg-like test apparatus and presents quantitative results on the accuracy and drift behaviour of these sensors in both static and dynamic conditions required for compression therapy. Extensive experimental work on this new human-leg-like test setup demonstrated its utility for evaluating the sensors. Results showed variation in static and dynamic sensing performance, including accuracy and drift characteristics. Only one commercially available pressure sensor was found to reliably deliver accuracy of 95% and above for all three test pressure points of 30, 50 and 70 mmHg.

54 citations

Journal ArticleDOI
TL;DR: The design, manufacture, and validation of the first circumferentially contractile and topographic self-fitting garments composed of NiTi-based shape memory alloy (SMA) knitted actuators that dynamically conform to the unique shape and size of the wearer's body in response to a change of the garment's temperature is introduced.
Abstract: Advances in actuating fabrics can enable a paradigm shift in the field of smart wearables by dynamically fitting themselves to the unique topography of the human body. Applications including soft wearable robotics, continuous health monitoring, and body-mounted haptic feedback systems are dependent upon simultaneous body proximity and garment stiffness for functionality. Passive fabrics and fitting mechanisms are unable to conform around surface concavities and require either high elasticity or a multiplicity of closure devices to achieve garment fit. The design, manufacture, and validation of the first circumferentially contractile and topographic self-fitting garments composed of NiTi-based shape memory alloy (SMA) knitted actuators that dynamically conform to the unique shape and size of the wearer's body in response to a change of the garment's temperature is introduced. Advanced materials and systems innovations 1) enable novel garment manufacturing and application strategies, 2) facilitate topographical fitting (spatial actuation) through garment architectural design, and 3) provide tunable NiTi-based SMA actuation temperatures to enable actuation on the surface of human skin. This research represents a paradigm shift for wearable applications by redefining garment fit to fully topographical conformation to the wearer through advanced materials and structures design.

47 citations

References
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PatentDOI
TL;DR: A very broad, additional spectrum of possible applications for intelligent polymers that covers an area from minimally invasive surgery, through high-performance textiles, up to self-repairing plastic components in every kind of transportation vehicles.
Abstract: Shape memory polymer compositions, articles of manufacture thereof, and methods of preparation and use thereof are described. The shape memory polymer compositions can hold more than one shape in memory. Suitable compositions include at least one hard segment and at least one soft segment. The Ttrans of the hard segment is preferably between -30 and 270 °C. At least one of the hard or soft segments can contain a cross-linkable group, and the segments can be linked by formation of an interpenetrating network or a semi-interpenetrating network, or by physical interactions of the blocks. Objects can be formed into a given shape at a temperature above the Ttrans of the hard segment, and cooled to a temperature below the Ttrans of the soft segment. If the object is subsequently formed into a second shape, the object can return to its original shape by heating the object above the Ttrans of the soft segment and below the Ttrans of the hard segment. The compositions can also include two soft segments which are linked via functional groups which are cleaved in response to application of light, electric field, magnetic field or ultrasound. The cleavage of these groups causes the object to return to its original shape.

2,837 citations


"Smart medical stocking using memory..." refers background in this paper

  • ...First, the deformation of SMPU is largely governed by entropy elasticity [37] and thus the rubber theories are expected to be valid to it....

    [...]

Journal ArticleDOI
TL;DR: Shape-memory polymers (SMPs) undergo significant macroscopic deformation upon the application of an external stimulus (e.g., heat, electricity, light, magnetism, moisture and even a change in pH value).

1,217 citations


"Smart medical stocking using memory..." refers methods in this paper

  • ...A thermal sensitive SMP has the potential to adjust the internal stress in its structure via external heating [29-31] and this characteristic is the key for the present case to obtain smart compression management as suggested by Laplace’s law [32-34]....

    [...]

Journal ArticleDOI
TL;DR: A brief review on the current progress in stimuli-responsive shape memory materials can be found in this article, where the focus is on twofold, namely newly observed ones, and novel applications with great potential at present and in near future.

864 citations

Reference EntryDOI
15 Mar 2002
TL;DR: In this paper, the shape-memory effect of polymers is defined as the ability of a polymeric material to memorize its permanent shape after exposure to an external stimulus, which is referred to as the one-way shape memory effect.
Abstract: Shape-memory polymers are stimuli-responsive materials. Upon exposure to an external stimulus, they have the capability of changing their shape. A change in shape initiated by a change in temperature is called thermally induced shape-memory effect. The shape-memory effect results from the polymer's structure, that is, its morphology in combination with a certain processing and programming technology. The polymer is processed into its permanent shape by conventional methods. Afterwards, it is deformed and the desired temporary shape is fixed. The latter process is called programming. Heating the programmed polymer above a temperature higher than the transition temperature Ttrans results in activating the shape-memory effect. As a consequence, the recovery of the memorized, permanent shape can be observed. The described effect is called a “one-way” shape-memory effect. The shape-memory effect can be quantified by cyclic thermomechanical investigations. Important quantities describing the shape-memory properties of the material for a certain strain ɛm are the strain recovery rate Rr and the strain fixity rate Rf. The strain recovery rate Rr quantifies the ability of the material to memorize its permanent shape. The strain fixity rate Rf describes the ability of the material to fix the mechanical deformation ɛm which has been applied during the programming process. Keywords: block copolymers; elastomers; networks; shape-memory polymers; stimuli-sensitive polymers; structure–property relations

816 citations

Frequently Asked Questions (13)
Q1. What have the authors contributed in "Smart medical stocking using memory polymer for chronic venous disorders" ?

This work aims to investigate and design a smart compression stocking using shape-memory polymer that allows externally controlling the pressure level in the wrapped position on the leg. The authors then presented a case where such a stocking is developed using a blend yarn consists of selected shape-memory polyurethane and nylon filaments. 

Future work in SMP should be done to examine several other factors, e. g., different SMPs, hard segment content, etc. 

Because of the internal stress and heat stimuli connection of SMPU materials,stockings with massage effect can be easily developed if a programmed heating source is incorporated into the system. 

If the authors can find a material whose internal stress σ can be easily adjusted in such that it can compensate the deviations of thepressure from the initially designated level, the authors can then sustain the desired pressure on the leg. 

On activating the stocking at greater temperature, the pressure increases to a higher level for the initial period (10 min), and thereafter starts decreasing. 

To sum up, the authors need a polymer material:1.   whose mechanical properties are sensitive enough to temperature changes of a narrowrange above the human body temperature;   8  2.   It obeys the rubber elasticity theories and, more specifically, follows Eqs. 5c or 6:during use of the stocking, an increase in temperature ΔT will lead to a sufficient increase in internal stress Δσ - hence a, b >0, and parameter b is sufficiently large; 3.   Also the selected material should be easy to process into stockings and comfort towear in contact with skin. 

The use of SMP film actuators may significantly obstruct the moisture transmission and the permeability of the compression system, and therefore not a viable solution for providing improved comfort to the patients. 

On the other hand, the internal stress in a stretched SMPU under constraint is caused by the entropic elasticity that will facilitate thermal contraction at high temperature. 

Patients suffering from chronic venous disorders, such as leg ulcers, oedema, venousstasis, venous hypertension, etc., are known to have poor quality of life due to continuous discomfort or pain, limited mobility and long recovery time, in addition to a rigorous management plan and thus the financial cost involved [1, 2]. 

SMPU filaments had shown a range of transition temperature (Fig. 3) due to the fact that not all the switching segments would activate altogether at a fixed temperature point. 

Table 3 shows that the stocking is able to generate extra pressure up to maximum of 16.2 mmHg by selecting suitable level of temperature and strain. 

Correlation of extra pressure and recovery stress   15  As suggested by Laplace’s law (or Eq. 7), the interface pressure depends on theinternal tension or stress developed in the stocking in the wrapped position. 

Once the stocking is applied to the leg, a tensile strain in the stocking, ε , is generated and can be calculated as,l s s C C C ε −= (1)Where lC and sC are the original circumferences of the leg and the stocking, respectively, and l sC C> .