Soccer heading is associated with white matter microstructural and cognitive abnormalities
Michael L. Lipton,Namhee Kim,Molly E. Zimmerman,Mimi Kim,Walter F. Stewart,Craig A. Branch,Richard B. Lipton +6 more
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Heading is associated with abnormal white matter microstructure and with poorer neurocognitive performance and this relationship is not explained by a history of concussion.Abstract:
Our current study results suggest that a nonlinear relationship exists between exposure to heading during the previous year, as measured by the Einstein Heading Questionnaire, and both abnormal white matter microstructure and poorer neurocognitive performance on a memory test.read more
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The new neurometabolic cascade of concussion
TL;DR: Improved guidelines for clinical management of concussion may be formulated as the functional significance and duration of these postinjury neurometabolic derangements are better delineated.
Journal ArticleDOI
A systematic review of potential long-term effects of sport-related concussion.
Geoff Manley,Andrew Gardner,Kathryn J Schneider,Kevin M. Guskiewicz,Julian E. Bailes,Robert C. Cantu,Rudolph J. Castellani,Michael K. Turner,Barry D. Jordan,Christopher Randolph,Jiří Dvořák,K. Alix Hayden,Charles H. Tator,Paul McCrory,Grant L. Iverson +14 more
TL;DR: More research is needed to better understand the prevalence of chronic traumatic encephalopathy and other neurological conditions and diseases, and the extent to which they are related to concussions and/or repetitive neurotrauma sustained in sports.
Journal ArticleDOI
Cumulative Head Impact Exposure Predicts Later-Life Depression, Apathy, Executive Dysfunction, and Cognitive Impairment in Former High School and College Football Players
Philip H. Montenigro,Michael L. Alosco,Brett M. Martin,Daniel H. Daneshvar,Jesse Mez,Christine E. Chaisson,Christopher J. Nowinski,Rhoda Au,Ann C. McKee,Robert C. Cantu,McClean,Robert S. Stern,Yorghos Tripodis +12 more
TL;DR: A bivariate probit, instrumental variable model revealed a threshold dose-response relationship between the CHII and risk for later-life cognitive impairment, and greater predictive validity than other individual exposure metrics.
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The neuropathology of sport
TL;DR: The beneficial aspects of sports participation on psychological, emotional, physical and cognitive health are summarized, and some of the less common adverse neuropathological outcomes are analyzed, including concussion, second-impact syndrome, juvenile head trauma syndrome, catastrophic sudden death, and CTE.
Journal ArticleDOI
Military-related traumatic brain injury and neurodegeneration
Ann C. McKee,Meghan E. Robinson +1 more
TL;DR: Early changes of chronic traumatic encephalopathy are found in four young veterans of the Iraq and Afghanistan conflict who were exposed to explosive blast and in another young veteran who was repetitively concussed.
References
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TL;DR: Linear Mixed-Effects and Nonlinear Mixed-effects (NLME) models have been studied in the literature as mentioned in this paper, where the structure of grouped data has been used for fitting LME models.
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Sanford Weisberg,John Fox +1 more
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