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Book ChapterDOI

Soft Computing in Bioinformatics

01 Jan 2021-pp 431-446
TL;DR: In this paper, the authors explored the soft computing based techniques for bioinformatics and discussed the necessity of soft computing techniques and their compatibility for solving wide spectrum of bio-informatic related problems.
Abstract: In this chapter, we explored the soft computing based techniques for bioinformatics. Necessity of soft computing techniques and their compatibility for solving wide spectrum of bioinformatics related problems is reviewed. Basics of soft computing techniques are discussed and their relevancy in solving many bioinformatics based problems is also elaborated. Actual experimental results on two real world bioinformatics data demonstrated the efficacy of soft computing techniques over conventional one for biological data problems.
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Journal ArticleDOI
11 Jan 2010
TL;DR: A new approach for fuzzification of the feature sets obtained through Gabor wavelet transforms has been discussed and the feature vectors thus obtained are classified using a newly designed fuzzified MLP.
Abstract: In this work a novel method for human face recognition that is based on fuzzy neural network has been presented. Here, Gabor wavelet transformation is used for extraction of features from face images as it deals with images in spatial as well as in frequency domain to capture different local orientations and scales efficiently. In face recognition problem multilayer perceptron (MLP) has already been adopted owing to its efficiency, but it does not capture overlapping and nonlinear manifolds of faces which exhibit different variations in illumination, expression, pose, etc. A fuzzy MLP on the other hand performs better than an MLP because fuzzy MLP can identify decision surfaces in case of nonlinear overlapping classes, whereas an MLP is restricted to crisp boundaries only. In the present work, a new approach for fuzzification of the feature sets obtained through Gabor wavelet transforms has been discussed. The feature vectors thus obtained are classified using a newly designed fuzzified MLP. The system has been tested on a composite database (DB-C) consisting of the ORL face database and another face database created for this purpose and a recognition rate of 97.875% with fuzzy MLP against a recognition rate of only 81.25% with MLP whose feature vectors were also obtained through same Gabor wavelet transforms has been obtained.

46 citations

Journal ArticleDOI
Zhi-Xin Su1
TL;DR: A hybrid fuzzy approach is proposed, which assesses each alternative in terms of distance measure calculated by a modified VIKOR method as well as similarity measure calculatedby a modified gray relational analysis (GRA) method, to the positive ideal alternative and the negative ideal alternative.
Abstract: The paper investigates fuzzy multi-attribute group decision-making (FMAGDM) problems. The important weights of the attributes and the ratings of the alternatives with respect to each attribute provided by multiple decision-makers are described by the linguistic variables expressed in triangular fuzzy numbers or trapezoidal fuzzy numbers. A hybrid fuzzy approach is proposed, which assesses each alternative in terms of distance measure calculated by a modified VIKOR method as well as similarity measure calculated by a modified gray relational analysis (GRA) method, to the positive ideal alternative and the negative ideal alternative. A new relative closeness coefficient is established to rank alternatives by aggregating the distance and the similarity measures. Two numerical examples for reverse logistics applications are presented to illustrate the proposed method.

45 citations

Journal ArticleDOI
TL;DR: The computational tool antaRNA is presented, capable of compiling RNA sequences for a given structure that comply in addition with an adjustable full range objective GC-content distribution, specific sequence constraints and additional fuzzy structure constraints.
Abstract: Motivation: RNA sequence design is studied at least as long as the classical folding problem. Although for the latter the functional fold of an RNA molecule is to be found, inverse folding tries to identify RNA sequences that fold into a function-specific target structure. In combination with RNA-based biotechnology and synthetic biology, reliable RNA sequence design becomes a crucial step to generate novel biochemical components. Results: In this article, the computational tool antaRNA is presented. It is capable of compiling RNA sequences for a given structure that comply in addition with an adjustable full range objective GC-content distribution, specific sequence constraints and additional fuzzy structure constraints. antaRNA applies ant colony optimization meta-heuristics and its superior performance is shown on a biological datasets. Availability and implementation: http://www.bioinf.uni-freiburg.de/Software/antaRNA Contact: ed.grubierf-inu.kitamrofni@nefokcab Supplementary information: Supplementary data are available at Bioinformatics online.

40 citations

Journal ArticleDOI
TL;DR: This paper is interested in the classification of signal transients for the reliable monitoring and timely diagnosing of nuclear components and systems and the problem is tackled within a fuzzy clustering approach.

29 citations

Journal ArticleDOI
01 Nov 2002
TL;DR: An automated face recognition (AFR) system that contains two components: eye detection and face recognition is presented, based on invariant radial basis function (IRBF) networks and knowledge rules of facial topology.
Abstract: In this paper, we present an automated face recognition (AFR) system that contains two components: eye detection and face recognition. Based on invariant radial basis function (IRBF) networks and knowledge rules of facial topology, a hybrid neural method is proposed to localize human eyes and segment the face region from a scene. A dual eigenspaces method (DEM) is then developed to extract algebraic features of the face and perform the recognition task with a two-layer minimum distance classifier. Experimental results illustrate that the proposed system is effective and robust.

27 citations