Journal ArticleDOI
Solvent compatibility of poly(dimethylsiloxane)-based microfluidic devices.
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TLDR
This paper describes the compatibility of poly(dimethylsiloxane) (PDMS) with organic solvents; this compatibility is important in considering the potential of PDMS-based microfluidic devices in a number of applications, including that of microreactors for organic reactions.Abstract:
This paper describes the compatibility of poly(dimethylsiloxane) (PDMS) with organic solvents; this compatibility is important in considering the potential of PDMS-based microfluidic devices in a number of applications, including that of microreactors for organic reactions. We considered three aspects of compatibility: the swelling of PDMS in a solvent, the partitioning of solutes between a solvent and PDMS, and the dissolution of PDMS oligomers in a solvent. Of these three parameters that determine the compatibility of PDMS with a solvent, the swelling of PDMS had the greatest influence. Experimental measurements of swelling were correlated with the solubility parameter, δ (cal1/2 cm-3/2), which is based on the cohesive energy densities, c (cal/cm3), of the materials. Solvents that swelled PDMS the least included water, nitromethane, dimethyl sulfoxide, ethylene glycol, perfluorotributylamine, perfluorodecalin, acetonitrile, and propylene carbonate; solvents that swelled PDMS the most were diisopropylam...read more
Citations
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The origins and the future of microfluidics
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Self-assembled monolayers of thiolates on metals as a form of nanotechnology.
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The present and future role of microfluidics in biomedical research
TL;DR: The progress made by lab-on-a-chip microtechnologies in recent years is analyzed, and the clinical and research areas in which they have made the greatest impact are discussed.
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New approaches to nanofabrication: molding, printing, and other techniques.
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Characterization of polydimethylsiloxane (PDMS) properties for biomedical micro/nanosystems.
TL;DR: PDMS surface hydrophilicity and micro-textures were generally unaffected when exposed to the different chemicals, except for micro-texture changes after immersion in potassium hydroxide and buffered hydrofluoric, nitric, sulfuric, and hydrofluic acids.
References
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Journal ArticleDOI
Fabrication of microfluidic systems in poly(dimethylsiloxane)
J.C. McDonald,David C. Duffy,Janelle R. Anderson,Daniel T. Chiu,Hongkai Wu,Olivier Schueller,George M. Whitesides +6 more
TL;DR: Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes to devices that handle aqueous solutions.
Journal ArticleDOI
Chaotic Mixer for Microchannels
Abraham D. Stroock,Stephan K. W. Dertinger,Armand Ajdari,Igor Mezic,Howard A. Stone,George M. Whitesides +5 more
TL;DR: This work presents a passive method for mixing streams of steady pressure-driven flows in microchannels at low Reynolds number, and uses bas-relief structures on the floor of the channel that are easily fabricated with commonly used methods of planar lithography.
Journal ArticleDOI
Poly(dimethylsiloxane) as a material for fabricating microfluidic devices.
TL;DR: This Account summarizes techniques for fabrication and applications in biomedicine of microfluidic devices fabricated in poly(dimethylsiloxane) (PDMS).
BookDOI
Physical properties of polymers handbook
TL;DR: Theoretical models and simulations of polymers have been used to study the molecular dynamics of different molecular architectures and properties of polymeric networks and gels as discussed by the authors, including the properties of different types of networks.