Solvent-Free Microwave Enhanced Knoevenagel Condensation of Ethyl Cyanoacetate with Aldehydes
TL;DR: In this article, a high yielding and fast method of Knoevenagel condensation of ethyl cyanoacetate with various aldehydes under microwave irradiation using environment-friendly ammonium acetate in the absence of any solvent is described.
About: This article is published in Synthetic Communications.The article was published on 1999-08-01. It has received 54 citations till now. The article focuses on the topics: Knoevenagel condensation & Ammonium acetate.
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2,484 citations
TL;DR: A series of new fiber catalysts has been synthesized by aminating a commercially available polyacrylonitrile fiber with polyamines such as diethylenetriamine and triethylenetetramine as discussed by the authors.
114 citations
TL;DR: When milled together with calcite or fluorite, malononitrile and methyl cyanoacetate readily underwent Knovenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α-cyanocinnamic esters in good yield as mentioned in this paper.
100 citations
TL;DR: In this paper, a new fiber catalyst for Knoevenagel condensation has been prepared by aminating a commercially available polyacrylonitrile fiber with N,N-dimethyl-1,3-propanediamine.
93 citations
TL;DR: In this article, the synthesis, characterization and applications of guanidine supported on magnetic nanoparticles Fe 3 O 4 (MNPs-Guanidine) as a novel magnetically separable base nanocatalyst are described.
81 citations
References
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1,321 citations
TL;DR: The Knoevenagel condensation of carbonyl compounds with active methylene compounds was readily carried out with aluminium oxide as a catalyst as discussed by the authors, and was shown to work well in the presence of active methylenes.
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