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Some physico-chemical aspects of hydroxylapatite

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TLDR
A review of hydroxylapatite, a biological material of extensive contemporary inter-disciplinary research, can be found in this article, where the authors provide information on preparation techniques, characterization, isomorphous substitutions and solubility equilibria.
Abstract
A few significant physico-chemical aspects of hydroxylapatite, a biological material of extensive contemporary inter-disciplinary research, have been reviewed. Updated information on preparation techniques, characterization, isomorphous substitutions, and solubility equilibria is provided. Recent research trends and aspects which require further clarification have been emphasized.

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Citations
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Journal ArticleDOI

Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants

TL;DR: A review of the past, present, and future of the hydroxyapatite (HAp)-based biomaterials from the point of view of preparation of hard tissue replacement implants is presented in this paper.
Journal ArticleDOI

Bioceramics of calcium orthophosphates

Sergey V. Dorozhkin
- 01 Mar 2010 - 
TL;DR: Current biomedical applications of calcium orthophosphate bioceramics include replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmentation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery.
Journal ArticleDOI

Calcium Orthophosphates in Nature, Biology and Medicine

Sergey V. Dorozhkin
- 20 Apr 2009 - 
TL;DR: Calcium orthophosphates are of great significance for humankind and, in this paper, an overview on the current knowledge on this subject is provided.
Journal ArticleDOI

Synthesis, characterization and antimicrobial activity of copper and zinc-doped hydroxyapatite nanopowders

TL;DR: In this paper, the synthesis of copper and zinc-doped hydroxyapatite was done by neutralization method, which consists of dissolving CuO or ZnO in solution of H3PO4, and the slow addition to suspension of Ca(OH)2 for obtaining monophasic product.
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Osteoblast response to hydroxyapatite doped with divalent and trivalent cations.

TL;DR: Results provided the first evidence that osteoblasts, bone-forming cells, adhered and differentiated in response to HA doped with trivalent cations at earlier time points than either HA doping with divalent cations or undoped HA.
References
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Book

Phosphorus and its compounds

Van Wazer, +1 more
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Apatite Crystallites: Effects of Carbonate on Morphology

TL;DR: The interference of carbonate with the good crystallization of apatite, and its weakening effect on the bonds in the structure, increase the dissolution rate and the solubility, thereby presumably contributing to the susceptibility to caries of dental apatites containing carbonate.