scispace - formally typeset
Search or ask a question
Journal ArticleDOI

Stenting the ductus arteriosus: Case selection, technique and possible complications

01 Jan 2008-Annals of Pediatric Cardiology (Medknow Publications)-Vol. 1, Iss: 1, pp 38-45
TL;DR: Ductal stenting is an attractive alternative to conventional shunt surgery in duct dependent congenital heart disease as it avoids thoracotomy and its related problems and may be achieved safely and with considerably less difficulty than previously described.
Abstract: Ductal stenting is an attractive alternative to conventional shunt surgery in duct dependent congenital heart disease as it avoids thoracotomy and its related problems With today's generation of coronary stents which have better profile, flexibility and trackability, ductal stenting may be achieved safely and with considerably less difficulty than previously described As in Blalock-Taussig (BT) shunt, ductal stenting is indicated mainly in duct-dependent cyanotic lesions chiefly in the neonatal period Unlike the Patent ductus arteriosus (PDA) as an isolated lesion, the ductus in cyanotic heart disease has a remarkable morphologic variability The ductus tends to arise more proximally under the aortic arch, giving rise to a vertical ductus or occasionally it may arise from the subclavian artery It also tends to be long and sometimes very tortuous, rendering stent implantation technically impossible The ductus in these patients may also insert onto one of the branch pulmonary arteries with some stenosis at the site of insertion The ductus in Tetralogy of Fallot with pulmonary atresia (TOF-PA) tend to exhibit these morphologic features and to a lesser degree in transposition of great arteries with ventricular septal defect and pulmonary atresia (TGA-VSD-PA) and the more complex forms of univentricular hearts In the preliminary angiographic evaluation, it is important to delineate these morphologic features as the basis for case selection Ductal stenting may be done by the retrograde femoral artery route or the antegrade transvenous route depending on the ductus morphology and the underlying cardiac lesion The detailed techniques and essential hardware are described Finally, major potential complications of the procedure are described Acute stent thrombosis is the most serious and potentially catastrophic Emergent treatment with thrombolytic therapy and mechanical disruption of thrombus are required With proper case selection, appropriate technique and the right hardware ductal stenting provides reasonable short-medium term palliation in duct-dependent cyanotic heart disease
Citations
More filters
Journal ArticleDOI
TL;DR: In this article, infants born with cardiac abnormalities causing dependence on the arterial duct for pulmonary blood flow are often palliated with a shunt usually between the subclavian artery and either
Abstract: Background:Infants born with cardiac abnormalities causing dependence on the arterial duct for pulmonary blood flow are often palliated with a shunt usually between the subclavian artery and either

115 citations

Journal ArticleDOI
TL;DR: A brief overview of the history of Tetralogy of Fallot is presented, the treatment strategies currently used are described, and the long-term survival, residual lesions, and re-interventions following repair are outlined.
Abstract: Tetralogy of Fallot (ToF) is the most common type of cyanotic congenital heart disease. Since the first surgical repair in 1954, treatment has continuously improved. The treatment strategies currently used in the treatment of ToF result in excellent long-term survival (30 year survival ranges from 68.5% to 90.5%). However, residual problems such as right ventricular outflow tract obstruction, pulmonary regurgitation, and (ventricular) arrhythmia are common and often require re-interventions. Right ventricular dysfunction can be seen following longstanding pulmonary regurgitation and/or stenosis. Performing pulmonary valve replacement or relief of pulmonary stenosis before irreversible right ventricular dysfunction occurs is important, but determining the optimal timing of pulmonary valve replacement is challenging for several reasons. The biological mechanisms underlying dysfunction of the right ventricle as seen in longstanding pulmonary regurgitation are poorly understood. Different methods of assessing the right ventricle are used to predict impending dysfunction. The atrioventricular, ventriculo-arterial and interventricular interactions of the right ventricle play an important role in right ventricle performance, but are not fully elucidated. In this review we present a brief overview of the history of ToF, describe the treatment strategies currently used, and outline the long-term survival, residual lesions, and re-interventions following repair. We discuss important remaining challenges and present the current state of the art regarding these challenges.

71 citations

Journal ArticleDOI
TL;DR: Stenting for the PDA is an appropriate alternative to surgical shunt creation in many patients with duct-dependent circulation and in this sample, the two groups did not differ significantly in terms of outcome or mortality.
Abstract: This report aims to compare the researchers’ early experience with the safety, efficacy, short-term outcomes, and complications of patent ductus arteriosus (PDA) stents in neonates having duct-dependent pulmonary circulation with those of surgically created shunts. Between April 2009 and April 2011, 18 infants with duct-dependent pulmonary circulation underwent cardiac catheterization for PDA stenting as the first palliative procedure in a referral center. For comparison, 20 infants who underwent surgical aortopulmonary shunt placement in another center were used. Follow-up assessment included clinical examination, echocardiography, oxygen saturation, and cardiac catheterization studies. Access and stenting for the PDA were successful in 15 patients (83.3 %). The mean procedure time was 58.43 ± 41.25 min, and the mean fluoroscopy time was 18.81 ± 5.64 min. Three patients (20 %) in the stented group and 6 patients (30 %) in the surgical group died (P = 0.09). After a 6-month follow-up period, none of the patients had significant stent stenosis requiring reintervention. The oxygen saturation increase did not differ significantly between the two groups either immediately after the procedure or 6 months later (P > 0.5). The left pulmonary artery diameter, McGoon ratio, and Nakata index did not differ significantly between the two groups (P > 0.05), but the right pulmonary diameter was larger in the stented group (5.01 ± 0.45 vs 4.1 ± 0.49 mm; P = 0.0001). Stenting for the PDA is an appropriate alternative to surgical shunt creation in many patients with duct-dependent circulation. In our sample, the two groups did not differ significantly in terms of outcome or mortality.

44 citations


Cites background or methods from "Stenting the ductus arteriosus: Cas..."

  • ...Uncovered segments of the PDA have a propensity for constriction [1]....

    [...]

  • ...It is not known currently whether loading neonatal and infant patients with antiplatelet agents the day before the procedure would reduce this complication as it does for adults [1]....

    [...]

  • ...If the problem recurs, it is best to refer the patient for surgery [1]....

    [...]

  • ...Stenting of the patent ductus arteriosus (PDA) is an appropriate alternative as a first-stage palliation of certain congenital heart diseases [1, 4, 8, 10]....

    [...]

  • ...Thrombolytic therapy with streptokinase or recombinant tissue plasminogen activator also has been suggested [1]....

    [...]

Journal ArticleDOI
TL;DR: To devise a classification scheme for ductal morphology in patients with ductal dependent pulmonary blood flow (PBF) that can be used to assess outcomes.
Abstract: Objectives To devise a classification scheme for ductal morphology in patients with ductal dependent pulmonary blood flow (PBF) that can be used to assess outcomes. Background The impact of ductal morphology on outcomes following patent ductus arteriosus (PDA) stenting is not well defined. Methods Patients Results One hundred and five patients underwent PDA stenting. TI was Type I in 58, Type II in 24, and Type III in 23 PDAs, respectively. There was a significant association between ductal origin and vascular access site (p 1 stent did not differ based on TI. Greater TI was associated with pulmonary artery (PA) jailing (p = 0.003). Twelve (11.4%) patients underwent unplanned reintervention, more commonly with greater TI (p = 0.022) and PA jailing (p Conclusions The proposed qualitative and quantitative PDA morphology classification scheme may be helpful in anticipating outcomes in patients with ductal dependent PBF undergoing PDA stenting.

42 citations

Journal ArticleDOI
TL;DR: Duct stenting demonstrated comparable early mortality, lower medium-term mortality,Lower risk of procedural complications, and higher risk of reintervention compared with the Blalock-Taussig shunt.

27 citations

Related Papers (5)