Storage and Flow of Solids
01 Jan 1964-
About: The article was published on 1964-01-01 and is currently open access. It has received 585 citations till now. The article focuses on the topics: Flow (mathematics).
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TL;DR: In this paper, the concept of critical filling speed, which was proposed to characterize the flowability with special application to die filling, is evaluated and compared with other powder flow characterization techniques.
Abstract: Inter-tablet variations in composition and weight depend on the flowability of pharmaceutical formulations. In this study, the concept of critical filling speed, which was proposed to characterize the flowability with special application to die filling, is evaluated and compared with other powder flow characterization techniques. It has been found that the critical filling speed provides a consistent gauge of the powder flowability with the poured angle of repose, Carr index, Hausner ratio, and flow functions from shear cell testing. However, the mass flow rate and the time to discharge a certain amount of powder through flowmeters showed a different trend, indicating that different powder flow behaviors are involved in these tests. This implies it is necessary to employ a powder flowability measurement technique that mimics the powder flow behavior in the actual application.
23 citations
TL;DR: This analysis provided an enhanced understanding of the typical flow properties of pharmaceutical materials and characterised the current operating space as a process flow map which could be used to focus future development.
23 citations
TL;DR: In this article, the steady state flow of powders is defined as a continuous deformation of the material without volume change while the stresses at the specimen's boundaries remain constant, which is a crucial concept to investigate the powders' strength and flow properties.
Abstract: Steady state flow of powders is a crucial concept to investigate the powders’ strength and flow properties This state is defined as a continuous deformation of the material without volume change while the stresses at the specimen’s boundaries remain constant Recent investigations have shown that this state, especially for cohesive powders, is not always as constant as it should be by definition This paper presents experimental and numerical work, both for cohesive and non-cohesive powders The experimental part focuses on the use of different control strategies, leading to steady state flow of different quality Differences between steady state flow for cohesive and non-cohesive powders are shown
22 citations
TL;DR: In this paper, a flow index obtained from measurements in a rotating drum is directly correlated to the flow through hoppers, providing a predictive method for hopper design and a convenient experimental test for screening materials and determining their suitability for specific hopper systems.
22 citations
TL;DR: In this paper, the effect of adding 2% sodium caseinate plus 2% buttermilk powder (B2S2) or 4% BMP (BMP) on the Power Law consistency index of 16 to 30 weeks old Danbo cheeses was investigated.
22 citations