Storage and Flow of Solids
01 Jan 1964-
About: The article was published on 1964-01-01 and is currently open access. It has received 585 citations till now. The article focuses on the topics: Flow (mathematics).
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TL;DR: The gravitational displacement rheometer (GDR) is used to characterize the effects of formulation composition and environmental conditions (moisture) on flow properties of cohesive pharmaceutical powders under unconfined conditions and captures the effect of lubricant concentration on the cohesion of powders.
105 citations
TL;DR: The relationship between mixing and demixing processes and the external and interparticle forces responsible for causing or opposing relative motion is reviewed in this article, where specific examples of mixing and segregation in flow over surfaces, in rotating cylinders and other applications are described.
Abstract: Mixing in powders generally results from relative motion of groups of particles ‒ convective mixing ‒ or of individuals ‒ dif fusive mixing. Segregation or demixing occurs when the motion of individual particles is biased according to their particular characteristics ‒ size, shape, composition etc. In the absence of such bias, individual motion invariably leads to homogenization of the mixture. Relationships between mixing/segregation processes and the external and interparticle forces responsible for causing or opposing relative motion are reviewed. Specific examples of mixing and segregation in flow over surfaces, in rotating cylinders and other applications are described.
103 citations
TL;DR: The advantages of mass-flow bins were first brought to the attention of engineers some ten years ago and a significant number of such bins have been installed, primarily in the U.S.A. but also in other countries.
103 citations
TL;DR: In this article, the fundamentals of cohesive powder consolidation and flow behavior are explained to combine reasonably particle and continuum mechanics, and the influence of elastic-plastic repulsion and, consequently, stressing pre-history dependent adhesion is demonstrated by the new model "stiff particles with soft contacts" and the contact force equilibrium.
Abstract: The fundamentals of cohesive powder consolidation and flow behaviour are explained to combine reasonably particle and continuum mechanics. The influence of elastic-plastic repulsion and, consequently, stressing pre-history dependent adhesion is demonstrated by the new model “stiff particles with soft contacts” and the contact force equilibrium. With this as the physical basis, incipient powder consolidation, yield and cohesive steady-state flow are explained. These models are used to evaluate shear cell test results as constitutive functions for computer aided apparatus design for reliable flow.
102 citations
TL;DR: It is shown that powder flow can be substantially improved by reducing the cohesion of powders by coating them with nanosized guest particles, and that comilling is an efficient process for nanocoating.
102 citations