Strategies to prevent hydrolytic degradation of the hybrid layer—A review
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Cites background from "Strategies to prevent hydrolytic de..."
...In general, these bonds show good durability, but are still prone to loss of bond strength with time [182]....
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...[182] Tjäderhane L, Nascimento FD, Breschi L, Mazzoni A, Tersariol ILS, Geraldeli S, et al....
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Cites background or methods or result from "Strategies to prevent hydrolytic de..."
...Glutaraldehyde is a widely known cross-linker that has been used in dental products, but its cytotoxicity seriously limits its clinical use.(6,120) Carbodiimide hydrochloride has very low cytotoxicity but may have limited cross-linking capacity....
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...Together, these would lead to improved bond durability.(1,6) Currently, however, technique sensitivity and generally long treatment times prohibit ethanol-wet bonding in clinical settings, and more user-friendly and reproducible techniques or materials need to be developed for everyday use....
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...degradation to preserve bond strength, chlorhexidine being the most popular compound.(6) Chlorhex-...
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...Collectively, the in vitro and in vivo data indicate that MDPB-containing adhesives may be superior in the prevention of bond strength loss, when compared to other SE adhesives.(6,60,64,67,104)...
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...integrity of the adhesive interface and the durability of the bond strength.(1,6) Biodegradation of resindentin interfaces also increases bacterial microleakage,(7) leading to undetected secondary caries....
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References
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"Strategies to prevent hydrolytic de..." refers background in this paper
...Since MMPs require calcium to maintain their tertiary structure and zinc ions for their catalytic activity [42] also in dentin [43], and CHX loses its MMP inhibition in the presence of calcium chloride [3], CHX-related MMP inhibition may be related to its chelating property and calcium ions released by the primer...
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