Stress-induced inhibition of sexual behavior: corticosterone inhibits courtship behaviors of a male amphibian (Taricha granulosa).
TL;DR: The hypothesis that elevated levels of corticosterone associated with exposure to stressful stimuli inhibit sexual behaviors in rough-skinned newts is supported.
About: This article is published in Hormones and Behavior.The article was published on 1984-12-01. It has received 262 citations till now. The article focuses on the topics: Corticosterone & Courtship display.
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TL;DR: Field work reveals that changes in responsiveness to LPFs have ecological bases, such as reproductive state, body condition etc., that in turn indicate different hormonal control mechanisms in the HPA cascade.
Abstract: SYNOPSIS. Superimposed upon seasonal changes in morphology, physiology and behavior, are facultative responses to unpredictable events known as labile ( i.e. , short-lived) perturbation factors (LPFs). These responses include behavioral and physiological changes that enhance survival and collectively make up the “emergency” life history stage. There is considerable evidence that glucocorticosteroids, and other hormones in the hypothalamo—pituitary—adrenal (HPA) cascade, initiate and orchestrate the emergency life history stage within minutes to hours. This stage has a number of sub—stages that promote survival and avoid potential deleterious effects of stress that may result from chronically elevated levels of circulating glucocorticosteroids over days and weeks. These sub—stages may include: redirection of behavior from a normal life history stage to increased foraging, irruptivetype migration during the day, enhanced restfulness at night, and elevated gluconeogenesis. Once the perturbation passes, glucocorticosteroids may also promote recovery. Additional evidence from birds indicates that glucocorticosteroid responses to a standardized capture, handling and restraint protocol are modulated both on seasonal and individual levels. Field work reveals that these changes in responsiveness to LPFs have ecological bases, such as reproductive state, body condition etc., that in turn indicate different hormonal control mechanisms in the HPA cascade.
1,269 citations
Cites background from "Stress-induced inhibition of sexual..."
...Subcutaneous injection of corticosterone profoundly inhibits courtship behavior in male rough-skinned newts, Taricha granulosa (Moore and Miller, 1984)....
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TL;DR: The field of birds in urban environments has been a hot topic in the last few decades as discussed by the authors, with a large body of work focusing on the effects of urbanization on birds.
Abstract: Preface. Section 1: Introduction to the Study of Birds in Urban Environments. 1. A historical perspective on urban bird research: trends, terms, and approaches J.M. Marzluff, R. Bowman, R. Donnelly. 2. Worldwide urbanization and its effects on birds J.M. Marzluff. 3. Synanthropic birds of North America R.F. Johnston. 4. Human perception and appreciation of birds: A motivation for wildlife conservation in urban environments of France P. Clergeau, G. Mennechez, A. Sauvage, A. Lemoine. 5. Quantifying the urban gradient: linking urban planning and ecology M. Alberti, E. Botsford, A. Cohen. 6. Urbanization, avian communities, and landscape ecology J.R. Miller, J.M. Fraterrigo, N. Thompson Hobbs, D.M. Theobald, J.A. Wiens. 7. The importance of multi-scale analyses in avian habitat selection studies in urban environments M. Hostetler. Section 2: Processes Affecting Birds in Urban Environments. 8. Urban birds: Population, community, and landscape approaches D. Bolger. 9. Interactions among non-native plants and birds S. Hayden Reichard, L. Chalker-Scott, S. Buchanan. 10. Urban sprawl and juniper encroachment effects on abundance of wintering passerines in Oklahoma B.R. Coppedge, D.M. Engle, S.D. Fuhlendorf, R.E. Masters, M.S. Gregory. 11. Nest predator abundance and urbanization D.G. Haskell, A.M. Knupp, M.C. Schneider. 12. Bird tolerance to human disturbance in urban parks of Madrid (Spain): Management implications E. Fernandez-Juricic, M.D. Jiminez, E. Lucas. 13. Settlement of breeding European Starlings in urban areas: importance oflawns vs. anthropogenic wastes G. Mennechez, P. Clergeau. 14. Variation in the timing of breeding between suburban and wildland Florida Scrub-Jays: Do physiologic measures reflect different environments? S.J. Schoech, R. Bowman. Section 3: Bird Populations in Urban Environments. 15. The ecology of Western Gulls in habitats varying in degree of urban influence R. Pierotti, C. Annett. 16. Causes and consequences of expanding American Crow populations J.M. Marzluff, K.J. McGowan, R. Donnelly, R.L. Knight. 17. Demographic and behavioral comparisons of suburban and rural American Crows K. McGowan. 18. Nest success and the timing of nest failure of Florida Scrub-Jays in suburban and wildland habitats R. Bowman, G.E. Woolfenden. 19. Synurbanization of the Magpie in the Palearctic L. Jerzak. 20. Maccaw abundance in relation to human population density in the western Amazon basin D.M. Brooks, A.J. Begazo. 21. Waterbird production in an urban center in Alaska M.R. North. Section 4: Bird Communities in Urban Environments. 22. Creating a homogeneous avifauna R.B. Blair. 23. Avian community characteristics of urban greenspaces in St. Louis, Missouri J.M. Azerrad, C.H. Nilon. 24. The importance of the Chicago region and the 'Chicago Wilderness' initiative for avian conservation J.D. Brawn, D.F. Stotz. 25. Do temporal trends in Christmas Bird Counts reflect the spatial trends of urbanization in southwestern Ohio? N.A. Crosby, R.B. Blair. 26. Survey techniques and habitat relationships of breeding birds in residential areas of Toronto, Canad
931 citations
TL;DR: It is argued that biological actions of GCs at "non-stress" seasonal concentrations play a critical role in the adjustment of responses that accompany predictable variability in the environment and demand more careful consideration in future studies.
755 citations
TL;DR: It appears that brain membranes contain a corticosteroid receptor that could participate in the regulation of behavior, and these binding sites were localized by receptor autoradiography in the neuropil, outside the regions of perikarya.
Abstract: Steroids may rapidly alter neuronal function and behavior through poorly characterized, direct actions on neuronal membranes. The membrane-bound receptors mediating these behavioral responses have not been identified. [3H]Corticosterone labels a population of specific, high-affinity recognition sites (dissociation constant = 0.51 nanomolar) in synaptic membranes from an amphibian brain. These binding sites were localized by receptor autoradiography in the neuropil, outside the regions of perikarya. The affinities of corticoids for this [3H]corticosterone binding site were linearly related to their potencies in rapidly suppressing male reproductive behavior. Thus, it appears that brain membranes contain a corticosteroid receptor that could participate in the regulation of behavior.
531 citations
TL;DR: It is suggested that several ecologically based ideas, such as variability in the length of the breeding season and lifetime reproductive opportunities, can be used to explain the utility of adrenocortical modulation in amphibian and reptilian species.
504 citations
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...Moore and Miller, 1984)....
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References
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TL;DR: A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like and β-endorphinlike immunoactivities by cultured anterior pituitary cells has been purified in this paper.
Abstract: A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like and β-endorphin-like immunoactivities by cultured anterior pituitary cells has been purified f...
4,335 citations
TL;DR: The data suggest that CRF may play a physiological role in the regulation of the hypothalamic-pituitary-adrenal axis.
Abstract: A 41-residue peptide purified as a corticotropin-releasing factor/beta-endorphin-releasing factor (CRF) in vitro was tested for its ability to stimulate the secretion of ACTH, beta-endorphin, and corticosterone in three animal groups: 1) unanesthesized rats bearing indwelling venous cannulae, 2) rats pretreated with chloropromazine plus morphine sulfate plus pentobarbital (CPZ-MS-Nb, and 3) rats with hypothalamic deafferentiations in the frontal and lateral retrochiasmatic areas. In all three bioassays iv administration of 0.1-10 micrograms CRF elicited a dose-related increase in plasma ACTH and beta-endorphin values over a 5- to 15-min period. Corticosterone secretion was also elevated but responded maximally with all doses of CRF tested. Pretreatment of CPZ-MS-Nb animals with 20 micrograms dexamethasone 4 h before assay abolished the CRF-induced hormone secretion. These data suggest that CRF may play a physiological role in the regulation of the hypothalamic-pituitary-adrenal axis.
560 citations
TL;DR: The first evidence for neurally placed CRF in the control of a specific hormone-dependent behavioural response is provided and an extremely potent suppressive effect of CRF is demonstrated on sexual behaviour in the female rat when microinfused into the arcuate–ventromedial area of the hypothalamus and the mesencephalic central grey.
Abstract: Corticotropin-releasing factor (CRF), the recently characterized and synthesized 41-amino acid polypeptide1,2 isolated from ovine hypothalami, has been shown to be a potent stimulator of adenohypophyseal β-endorphin and corticotropin (ACTH) secretion both in vitro2,6 and in vivo2,4,7,8. In common with other regulatory peptides, CRF has also been demonstrated to possess extra-hypophysiotropic roles. Indeed, intracerebroventricularly (i.c.v.) administered CRF elicits several endocrine and behavioural responses compatible with the concept that this peptide could be a key signal in coordinating the organism's endocrine and behavioural responses to stressful and other adaptive stimuli8–14. We now provide the first evidence for neurally placed CRF in the control of a specific hormone-dependent behavioural response and unequivocally demonstrate an extremely potent suppressive effect of CRF on sexual behaviour in the female rat when microinfused into the arcuate–ventromedial area of the hypothalamus (ARC–VMH) and the mesencephalic central grey (MCG).
288 citations
"Stress-induced inhibition of sexual..." refers background in this paper
...In female rats, an icv infusion of P-endorphin or CRF promptly and significantly inhibits lordosis and an infusion of anti-P-endorphin antiserum potentiates lordosis (Sirinathsinghji et al., 1983a; Sirinathsinghji, Whittington, AudsIey, and Fraser, 1983b)....
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Journal Article•
259 citations
"Stress-induced inhibition of sexual..." refers background in this paper
...Sexual dysfunction in stressed animals has been the subject of some studies (reviewed by Christian, Lloyd, and Davis, 1965; Kime, Vinson, Major, and Kilpatrick, 1980; Nowell, 1980), but very little is known about the specific physiological mechanisms whereby stress inhibits sexual behavior....
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