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Structural and synthetic studies on the retrofractamides—amide constituents of Piper retrofractum

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TLDR
In this article, two unsaturated amides, retrofractamides A and C, were isolated from the total aboveground parts of Piper retroractum and were shown to be N -isobutyl-9(3′,4′-methylenedioxyphenyl)2 E,4 E,8 E -nonatrienamide from spectroscopic and chemical investigations.
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This article is published in Phytochemistry.The article was published on 1985-02-05. It has received 42 citations till now. The article focuses on the topics: Piper retrofractum.

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Phytochemistry of the genus Piper

TL;DR: The secondary metabolites isolated from Piper species for the period 1907 to June 1996 have been reviewed in this paper, where nearly six hundred chemical constituents belonging to different classes of bioactive compounds are listed together with their source(s) and references.
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Larvicidal activity of isobutylamides identified in Piper nigrum fruits against three mosquito species

TL;DR: Structural-activity relationships indicate that the N-isobutylamine moiety might play a crucial role in the larvicidal activity, but the methylenedioxyphenyl moiety does not appear essential for toxicity.
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Constituents of Chinese Piper species and their inhibitory activity on prostaglandin and leukotriene biosynthesis in vitro.

TL;DR: The n-hexane extracts of 19 Piper species, predominantly from China, were screened for their 5-lipoxygenase (5-LOX) and cyclo oxygengenase-1 (COX-1) inhibitory potential and showed considerable inhibitory activity against at least one of these two key enzymes of the arachidonic acid metabolism.
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Alkaloids of Piper longum Linn—I : Structure and synthesis of piperlongumine and piperlonguminine

TL;DR: Piperlongumine and piperlonguminine are shown to be N-(3,4,5-trimethoxycinnamoyl)-Δ5-piperidin-2-one and isobutylamide of piperic acid respectively.
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