scispace - formally typeset
Search or ask a question
Journal ArticleDOI

Studies of Modern Man

01 Oct 1972-Annual Review of Anthropology (Annual Reviews 4139 El Camino Way, P.O. Box 10139, Palo Alto, CA 94303-0139, USA)-Vol. 1, Iss: 1, pp 55-112
TL;DR: A review of studies in the physical anthropology of modern man concerns papers that have appeared in the period from mid-1969 to mid-1971 as mentioned in this paper, and aims to show how much activity there is in each major topic of investigation in the biological study of populations of man.
Abstract: This review of studies in the physical anthropology of modern man concerns papers that have appeared in the period from mid-1969 to mid-1971. Though far from comprehensive it aims to show how much activity there is in each major topic of investigation in the biological study of populations of man that exist today, and to pick out any trends in investigation that may be detectable. Several topics have been intentionally excluded, e.g. behavior studies, psychometric investigations, descriptive osteometry, and epidemiological works relating to particular disease states.
Citations
More filters
Journal ArticleDOI
TL;DR: The article demonstrates the need for future public health policies to take new geographic and ecological concepts, such as the pathogenic complex, epidemiological landscape or pathocenosis, need to be integrated into the medical reasoning process.

8 citations

Dissertation
10 Nov 2011
TL;DR: La malnutrition maternelle constitue une part importante dans l'etiologie de the restriction de croissance intra-uterine (RCIU), nous avons utilise un modele experimental effectue chez le rat, qui consiste en une reduction (de 50% a 70%) of the ration alimentaire quotidienne maternelsle durant the gestation.
Abstract: De nombreuses donnees indiquent qu’un petit poids a la naissance, resultant en partie d’une sous-nutrition materno-fœtale, est associe a une augmentation de la morbidite et de la mortalite durant la periode neonatale, et conduit egalement a un risque accru de developper a l'âge adulte un syndrome metabolique (diabete de type 2, obesite, hypertension arterielle et dyslipidemie). Les mecanismes de cette programmation prenatale sont encore mal connus et impliqueraient plusieurs molecules et systemes physiologiques distincts. De nombreuses etudes suggerent que le placenta serait implique dans la programmations de ces pathologies metaboliques. En effet, celui-ci constitue un organe de communication entre la mere et son fœtus et participe a la regulation de l'homeostasie fœtale. En raison de la proportion croissante de femmes presentant des troubles de la nutrition durant la grossesse et en lien avec leurs repercussions potentielles chez la descendance, il est necessaire de mieux comprendre les interactions entre l’alimentation maternelle et l’unite fœto-placentaire et d’identifier les mecanismes impliques dans les alterations de la croissance fœtale. En consequent, le placenta constitue un organe de choix pour etudier les interactions entre l’alimentation maternelle et le fœtus au cours de la grossesse. Durant cette these, nous avons tente d’identifier de nouvelles voies moleculaires placentaires impliquees dans le controle de la croissance fœtale chez le rat, puis d'etudie l'expression de ces facteurs dans des placentas humains provenant de grossesses impliquant des anomalies de la croissance fœtale. Comme la malnutrition maternelle constitue une part importante dans l'etiologie de la restriction de croissance intra-uterine (RCIU), nous avons utilise un modele experimental effectue chez le rat, qui consiste en une reduction (de 50% a 70%) de la ration alimentaire quotidienne maternelle durant la gestation. Ces regimes conduisent a des troubles de la croissance de l'unite fœto-placentaire reveles par des reductions drastiques du poids du placenta et des poids de naissance a terme. Afin d'identifier de nouvelles voies placentaires impliquees dans RCIU, nous avons utilise deux methodologies differentes: une approche proteomique et une evaluation de deux proteines recemment caracterisees.Premierement, nous avons etudie le proteome placentaire chez le rat RCIU provenant de meres denutris par une analyse proteomique (2D-PAGE et spectrometrie de masse). Cette strategie nous a permis de decouvrir de nouvelles voies modulees par le RCIU et, etonnamment, des modulations importantes ont ete observees pour plusieurs proteines mitochondriales, suggerant un effet cible de la denutrition sur ces organites. Par la suite, en utilisant diverses techniques d'analyses moleculaires, proteomiques et fonctionnelles, nous avons montre que ces organites elaborent une reponse adaptative a la restriction alimentaire maternelle qui pourrait avoir des consequences sur la regulation de la croissance fœtale. Deuxiemement, nous avons etudie deux autres proteines atypiques: le brain-derived neurotrophic factor et l'hormone apeline. Nos resultats suggerent que ces deux facteurs pourraient etre impliques, au niveau placentaire, dans le controle de la croissance fœtale a la fois chez le rat et chez l'homme. En conclusion, comme les techniques cliniques actuelles ne permettent pas de diagnostiquer avec precision un RCIU, nos resultats pourraient permettre une meilleure comprehension de la physiopathologie placentaire et permettre de developper de nouveaux marqueurs de diagnostique et/ou de traitement dans le but d'ameliorer la croissance placentaire et fœtale en conditions pathologiques.

3 citations

References
More filters
Journal ArticleDOI
A. K. Kalla1
TL;DR: The forehead pigmentation was found to increase with age, so also was the forehead tanning but it was realised that from such studies it would be difficult to demarcate the effect of age on skin tanning.
Abstract: Skin reflectances were obtained at 426, 550 and 685mg wavelengths (employed in the E.E.L.spectrophotometer) from medial arm and forehead sites among 414“Baniya”males to study the changes in skin pigmentation with age during 10-16 years-an important growth period. It was not possible to arrive at any general conclusion using together the three reflectance scales-Log R426mμ, R550mμ, and“Anti-log”R685mμ, because they exhibited some significant differences in their results“Anti-log”R685mμ, scale was finally adopted to study this problem.The observations for the unexposed medial arm site were used as indicator of the changes in skin colour with age. It was found that during the period between 10 and 16 years, the males first exhibit an increase in the pigmentation which is then lost through the adolescent years even to a significant extent.The forehead pigmentation was found to increase with age, so also was the forehead tanning but it is realised that from such studies it would be difficult to demarcate the effect of age on skin tanning

8 citations

Journal ArticleDOI
TL;DR: Tests of work capacity as measured by O2 consumption, pulse rate, and ventilation rate are reported, suggesting the necessity of more precise definitions in studies of the physical activity of high altitude natives.
Abstract: Altitude adaptation was measured at sea level and high altitudes in sea level adapted and high altitude adapted natives. Tests of work capacity as measured by O2 consumption, pulse rate, and ventilation rate are reported. It is noted that comparing our results with those of other investigators is difficult due to variations in terminology and procedure. This suggests the necessity of more precise definitions in studies of the physical activity of high altitude natives.

8 citations

Journal ArticleDOI
TL;DR: The effects of parental consanguinity, age, and sex on defects of the eye and ear, accomodation, mean visual acuity, and mean decibels of hearing loss at four frequencies have been investigated in a series of Middle School children and their parents on Hirado Island, Japan.
Abstract: The effects of parental consanguinity, age, and sex on defects of the eye and ear, accomodation, mean visual acuity, and mean decibels of hearing loss at four frequencies have been investigated in a series of Middle School children and their parents on Hirado Island, Japan. In the children the effect of paternal and maternal inbreeding on these same indicators has also been investigated. The numbers available for the various analyses after eliminations for incompleteness of records, and confining the analysis to children where socioeconomic data are complete, are given in table III. Age and sex effects are encountered at high levels of statistical significance, but, unlike the results on Hirado with respect to a variety of other indicators [Schull et al., 1970; Neel et al., 1970], socioeconomic effects are negligible. None of the regressions on consanguinity or inbreeding is individually significant, nor is there any consistent pattern to the totality of the regressions. On the other hand, the sampling errors are such that the data cannot be said to conflict with the significant positive findings regarding consanguinity effects in a previous study in Hiroshima and Nagasaki [Schull and Neel, 1965].

8 citations