Journal ArticleDOI
Suppression of annual testicular development in Indian Palm Squirrel, Funambulus pennanti by 8 hr temporal relationship of serotonin and dopamine precursor drugs
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TLDR
Results indicate that induced suppression of gonadal function in a fashion similar to seasonal regression leading to non-breeding condition is the consequence of specific phase relationship (8 hr) between serotonergic and dopaminergic activities and not due to Serotonin or dopamine alone.Abstract:
Daily injections of 5-HTP (5-hydroxytryptophan, serotonin precursor) and L-DOPA (L-Dihydroxyphenylalanine, dopamine precursor) given 8 hour apart inhibited normal testicular growth in seasonally breeding Indian Palm Squirrel,Funambuluspennanti leading to complete gonadal atrophy, which was maintained till the end of the study. HCG administration induced higher degree of gonadal development but, when the two treatments (HCG + 8 hr relationship of 5-HTP and L-DOPA) were given simultaneously no significant difference was observed compared to control.read more
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Four Hour Temporal Relation of 5-HTP and L-DOPA Induces Inhibitory Responses in Recrudescing Gonad of Indian Palm Squirrel (Funambulus pennantii).
TL;DR: It is apparent that seasonal testicular recrudescence of Indian palm squirrel during short day length by 4 h relation of 5-HTP and L-DOPA is not a pharmacological effect but actually is an alteration of seasonality in this annually breeding mammal.
Journal ArticleDOI
Temporal Phase Relation of Serotonergic and Dopaminergic Oscillations Alters Seasonal Reproduction and Adrenal Function in Jungle Bush Quail and Rain Quail~!2009-01-06~!2009-02-02~!2009-04-09~!
TL;DR: It is concluded that specific relation of serotonergic and dopaminergic oscillation induces reproductively quiescent or active condition out of the season as a function of their time relation and suggests that, circadian organization may regulate reproductive and metabolic seasonality irrespective of the phase of the annual gonadal cycle.
Journal Article
Temporal Phase Relation of Serotonergic and Dopaminergic OscillationsAlters Seasonal Reproduction and Adrenal Function in Jungle Bush Quailand Rain Quail
TL;DR: It is concluded that specific relation of serotonergic and dopaminergic oscillation induces reproductively quiescent or active condition out of the season as a function of their time relation and suggests that, circadian organization may regulate reproductive and metabolic seasonality irrespective of the phase of the annual gonadal cycle.
References
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Journal ArticleDOI
The Pineal and Its Hormones in the Control of Reproduction in Mammals
TL;DR: By the usual criteria in endocrinology, the pineal now fulfills all the qualifications of an organ of internal secretion.
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Differential projections of the nucleus raphe dorsalis and nucleus raphe centralis as revealed by autoradiography.
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dl‐5‐Hydroxytryptophan‐induced changes in central monoamine neurons after peripheral decarboxylase inhibition*
TL;DR: The ability of the 5‐ HT neurons to take up and accumulate 5‐HT in the presence of5‐HTP is relatively low in spite of large amounts of 5-HTP present in the brain neuropil after extracerebral decarboxylase inhibition.
Journal ArticleDOI
In vivo release of 5-HT in the lateral ventricle of the rat: effects of 5-hydroxytryptophan and tryptophan.
TL;DR: The results suggest that some relationships occurred between the changes in 5-HT SYNTHESIs and release after the first hour of perfusion and the absence of effects of tryptophan treatments on 5- HT release during the firsthour of perfusions are discussed.
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