Surface T-cell antigen receptor expression and availability for long-term antigenic signaling.
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...These findings are consistent with previous reports that TCR mRNA levels are stable [17]....
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"Surface T-cell antigen receptor exp..." refers background in this paper
...When Sousa and Carneiro (104) mathematically modeled the data of Valitutti et al. (95), they noticed the biphasic kinetics of TCR downregulation....
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...On the one hand, human T-cell clones (95), a murine T-cell hybridoma (106), and naı̈ve CD4þ murine T cells (8) were shown to only...
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"Surface T-cell antigen receptor exp..." refers background in this paper
...However, both downregulation and upregulation of surface TCR level has been documented in activated T cells (109, 133, 134), consistent with the idea that active signal transduction can affect surface TCR expression level (Table 2)....
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