Patent•
Surgical instruments comprising a biased shifting mechanism
24 Aug 2018-
TL;DR: In this paper, a shiftable transmission for a surgical instrument comprising of a shift-able transmission is described, which comprises a mechanism for assuring that the transmission is in one of a plurality of predefined configurations.
Abstract: A surgical instrument comprising a shiftable transmission is disclosed. The transmission comprises a mechanism for assuring that the transmission is in one of a plurality of predefined configurations.
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Patent•
28 Jun 2017
TL;DR: In this paper, a shaft assembly is disclosed comprising a shaft including a proximal end, a distal end and a longitudinal axis extending between the proximal and distal ends.
Abstract: A shaft assembly is disclosed comprising a shaft including a proximal end, a distal end, a longitudinal axis extending between the proximal end and the distal end, and an outer housing comprising a shaft radius defined with respect to the longitudinal axis. The shaft assembly further comprises an end effector comprising an end effector frame rotatably coupled to the shaft about a fixed articulation axis positioned laterally offset with respect to the longitudinal axis. The shaft assembly further comprises an articulation driver coupled to the end effector frame at an attachment location, wherein a lateral moment arm is defined between the attachment location and the fixed articulation axis, wherein the lateral moment arm is orthogonal to the longitudinal axis, and wherein the shaft assembly is configured such that a ratio of the shaft radius to the lateral moment arm is minimized.
172 citations
Patent•
28 Jun 2017
TL;DR: In this article, the second jaw is pivotable relative to the first jaw about a pivot axis by an axially movable closure member, and a first distance between the pivot axis and an area of camming contact between a closure member cam surface on the closure member and a jaw cam surface is divided by a second distance from the articulation axis to the proximal most fastener location.
Abstract: A surgical instrument, comprising an articulatable end effector that is selectively articulatable about an articulation axis. The end effector comprises first and second jaws wherein the second jaw is pivotable relative to the first jaw about a pivot axis by an axially movable closure member. One of the first and second jaws supports a fastener cartridge that defines a proximal most fastener location therein. A first distance between the pivot axis and an area of camming contact between a closure member cam surface on the closure member and a jaw cam surface on one of the first and second jaws divided by a second distance from the articulation axis to the proximal most fastener location is less than 0.5.
172 citations
Patent•
29 Jun 2018
TL;DR: In this article, a surgical system includes a surgical instrument, an end-effector, a control circuit, and a sensor configured to transmit a sensor signal indicative of a closure parameter of the end effector.
Abstract: A surgical system includes a surgical instrument, an end effector, a control circuit, and a sensor configured to transmit a sensor signal indicative of a closure parameter of the end effector. The control circuit is configured to adjust a closure rate of change parameter and the closure threshold parameter based on perioperative information received from one or more data sources and a sensor signal received from the sensor.
32 citations
Patent•
29 Jun 2018
TL;DR: In this article, a control circuit is configured to determine a value of the tissue compression parameter via the sensor as the jaws transition from the open configuration to the closed configuration, which causes the motor to increase a time to transition the jaws to a closed configuration according to whether the value of tissue compression parameters is above a first threshold, and provide feedback when the value is below a second threshold.
Abstract: A surgical instrument includes an end effector, a motor for opening and closing the jaws, a sensor configured to detect a tissue compression parameter associated with a tissue between the jaws, and a control circuit. The control circuit is configured to determine a value of the tissue compression parameter via the sensor as the jaws transition from the open configuration to the closed configuration, cause the motor to increase a time to transition the jaws to the closed configuration according to whether the value of the tissue compression parameter is above a first threshold, and provide feedback according to whether the value of the tissue compression parameter is below a second threshold.
30 citations
Patent•
24 Aug 2018
TL;DR: In this article, a handle assembly consisting of an actuation trigger and a curved cylinder surrounding it is described, and the curved cylinder comprises an electroactive polymer, which is responsive to the actuation force and provides feedback to a user.
Abstract: A surgical instrument system comprising a handle assembly is disclosed. The handle assembly comprises an actuation trigger comprising a curved proximal portion and a curved cylinder surrounding the curved proximal portion of the actuation trigger. The curved cylinder comprises an electroactive polymer. The surgical instrument system comprises an actuation rod which is configured to transmit an actuation force and a sensor system which is configured to detect the magnitude of the actuation force. The electroactive polymer is responsive to the actuation force and provides feedback to a user of the surgical instrument system.
28 citations
References
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TL;DR: It is proposed that the metabolism of cancer cells, and indeed all proliferating cells, is adapted to facilitate the uptake and incorporation of nutrients into the biomass needed to produce a new cell.
Abstract: In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative phosphorylation to generate the energy needed for cellular processes, most cancer cells instead rely on aerobic glycolysis, a phenomenon termed “the Warburg effect.” Aerobic glycolysis is an inefficient way to generate adenosine 5′-triphosphate (ATP), however, and the advantage it confers to cancer cells has been unclear. Here we propose that the metabolism of cancer cells, and indeed all proliferating cells, is adapted to facilitate the uptake and incorporation of nutrients into the biomass (e.g., nucleotides, amino acids, and lipids) needed to produce a new cell. Supporting this idea are recent studies showing that (i) several signaling pathways implicated in cell proliferation also regulate metabolic pathways that incorporate nutrients into biomass; and that (ii) certain cancer-associated mutations enable cancer cells to acquire and metabolize nutrients in a manner conducive to proliferation rather than efficient ATP production. A better understanding of the mechanistic links between cellular metabolism and growth control may ultimately lead to better treatments for human cancer.
12,380 citations
TL;DR: A comprehensive survey of the state-of-the-art MEC research with a focus on joint radio-and-computational resource management is provided in this paper, where a set of issues, challenges, and future research directions for MEC are discussed.
Abstract: Driven by the visions of Internet of Things and 5G communications, recent years have seen a paradigm shift in mobile computing, from the centralized mobile cloud computing toward mobile edge computing (MEC). The main feature of MEC is to push mobile computing, network control and storage to the network edges (e.g., base stations and access points) so as to enable computation-intensive and latency-critical applications at the resource-limited mobile devices. MEC promises dramatic reduction in latency and mobile energy consumption, tackling the key challenges for materializing 5G vision. The promised gains of MEC have motivated extensive efforts in both academia and industry on developing the technology. A main thrust of MEC research is to seamlessly merge the two disciplines of wireless communications and mobile computing, resulting in a wide-range of new designs ranging from techniques for computation offloading to network architectures. This paper provides a comprehensive survey of the state-of-the-art MEC research with a focus on joint radio-and-computational resource management. We also discuss a set of issues, challenges, and future research directions for MEC research, including MEC system deployment, cache-enabled MEC, mobility management for MEC, green MEC, as well as privacy-aware MEC. Advancements in these directions will facilitate the transformation of MEC from theory to practice. Finally, we introduce recent standardization efforts on MEC as well as some typical MEC application scenarios.
2,992 citations
Patent•
10 Jun 2011
TL;DR: In this article, a surgical stapling device particularly suited for endoscopic procedures is described, which includes a handle assembly and an elongated body extending distally from the handle assembly.
Abstract: A surgical stapling device particularly suited for endoscopic procedures is described The device includes a handle assembly and an elongated body extending distally from the handle assembly The distal end of the elongated body is adapted to engage a disposable loading unit A control rod having a proximal end operatively connected to the handle assembly includes a distal end extending through the elongated body A control rod locking member is provided to prevent movement of the control rod until the disposable loading unit is fully secured to the elongated body of the stapling device
2,013 citations
Patent•
22 Apr 1994
TL;DR: In this article, a surgical device for stapling and fastening body tissues, consisting of an insertion section extending from an operation section for insertion into a body cavity, and a stitching member connected to a distal end of the insertion section, for treating body tissues with a high-frequency current within the body cavity.
Abstract: A surgical device for stapling and fastening body tissues, comprises an insertion section extending from an operation section for insertion into a body cavity, stapling member connected to a distal end of the insertion section, for treating body tissues with a high-frequency current within a body cavity. The stapling member includes an anvil and a cartridge between which the tissues are sandwiched, and a cutter. Staples are applied to the anvil from the cartridge for stapling the tissues and the cutter cuts the tissue while it applies a high-frequency current thereto.
1,972 citations
Patent•
21 Jul 1994TL;DR: An electrosurgical instrument is provided for cauterization and/or welding of tissue of varying impedances, thicknesses and vascularity especially in the performance of endoscopic procedures as discussed by the authors.
Abstract: An electrosurgical instrument is provided for cauterization and/or welding of tissue of varying impedances, thicknesses and vascularity especially in the performance of endoscopic procedures. The instrument compresses the tissue between one pole of a bipolar energy source located on one interfacing surface, and a second interfacing surface. A second pole is located one of the two interfacing surfaces. In a preferred embodiment, the second pole is located on the same interfacing surface as the first pole and an insulator electrically isolates the two poles. A preferred application of the invention is in a cutting instrument wherein a hemostatic line is formed along a cut line using RF energy.
1,912 citations