scispace - formally typeset
Journal ArticleDOI

Survival Curve for Cancer Patients Following Treatment

Joseph Berkson, +1 more
- 01 Sep 1952 - 
- Vol. 47, Iss: 259, pp 501-515
Reads0
Chats0
TLDR
A simple function, in terms of two physically meaningful parameters, has been evolved, which fits survivorship data very well and can be used to compare succinctly the mortality of two groups, different in respect of treatment, type of cancer, or other characteristics.
Abstract
On the basis of experience with calculated survivorships of patients following treatment for cancer, a simple function, in terms of two physically meaningful parameters, has been evolved, which fits such survivorship data very well. These two parameters can be used to compare succinctly the mortality of two groups, different in respect of treatment, type of cancer, or other characteristics. The parameters are c (“cured”), which represents the proportion of the population which is subject only to “normal” death rates, and β, which is the death rate from the cancer, to which the rest of the population [not “cured,” (1–c)] is subject. Thus if one treatment is characterized by c 1 = 0.30, β 1 = 0.25, another by c 2 = 0.20, β 2 = 0.15, this could be interpreted as meaning that while the first treatment “cured” a larger proportion of the population than did the second treatment, it did not ameliorate the deaths attributable to cancer in the patients not cured as much as did the second treatment. If l T...

read more

Citations
More filters
Book ChapterDOI

Nonparametric Estimation from Incomplete Observations

TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Journal ArticleDOI

Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.

Claudia Allemani, +594 more
- 17 Mar 2018 - 
TL;DR: For most cancers, 5-year net survival remains among the highest in the world in the USA and Canada, in Australia and New Zealand, and in Finland, Iceland, Norway, and Sweden, while for many cancers, Denmark is closing the survival gap with the other Nordic countries.
Journal ArticleDOI

A New Bayesian Model For Survival Data With a Surviving Fraction

TL;DR: In this article, the authors consider right-censored survival data for populations with a surviving (cure) fraction and propose a model that is quite different from the standard mixture model for cure rates.
Related Papers (5)