Journal ArticleDOI
Synthesis and spectral data of 4,5-bis[5-aryl-1,3,4-oxadiazol-2-yl]-1-benzyl-1,2,3-triazoles
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TLDR
In this article, the synthesis of the title compounds 3 upon cyclodehydration with thionyl chloride of the corresponding bis-aroylhydrazides 2 is described and their spectral properties are examined.About:
This article is published in Journal of Heterocyclic Chemistry.The article was published on 1990-09-01. It has received 42 citations till now. The article focuses on the topics: Thionyl chloride & Aryl.read more
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An efficient synthesis and biological study of novel indolyl-1,3,4-oxadiazoles as potent anticancer agents
TL;DR: A facile, convenient and high yielding synthesis of a series of novel 5-(3'-indolyl)-2-(substituted)-1,3,4-oxadiazoles from readily available starting materials has been described.
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A facile procedure for the one-pot synthesis of unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles
TL;DR: In this paper, 2,5-disubstituted 1,3,4-oxadiazoles were efficiently synthesized from the cyclization-oxidation reaction of acyl hydrazones.
Journal ArticleDOI
Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines
Gabriel Navarrete-Vázquez,Gloria María Molina-Salinas,Zetel Vahi Duarte-Fajardo,Javier Vargas-Villarreal,Samuel Estrada-Soto,Francisco González-Salazar,Emanuel Hernández-Núñez,Salvador Said-Fernández +7 more
TL;DR: 4-(5-Substituted-1,3,4-oxadiazol-2-yl)pyridine derivatives 1-12 were synthesized and evaluated for their in vitro antimycobacterial activity, showing an interesting activity against Mycobacterium tuberculosis H(37)Rv and five clinical isolates.
Journal ArticleDOI
Microwave assisted one pot synthesis of some novel 2,5-disubstituted 1,3,4-oxadiazoles as antifungal agents.
TL;DR: Sodium bisulfite has been reported first time for the synthesis of 2,5-disubstituted 1,3,4-oxadiazole using microwave and conventional method in ethanol-water and some of the compounds were equipotent with miconazole against Candida albicans and Fusarium oxysporum.
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1,3,4-Oxadiazole: A Privileged Structure in Antiviral Agents
Zhuo Li,Peng Zhan,Xinyong Liu +2 more
TL;DR: The binding models of some representative 1,3,4-oxadiazoles were discussed, which provide rational explanation for their interesting antiviral activities, and also pave the way for further optimization of 1, 3, 4- oxadiazole based antiviral agents.
References
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Journal ArticleDOI
2,5-diaryloxazoles and 2,5-diaryl-1,3,4-oxadiazoles
Journal ArticleDOI
Zur acylierung von 5-aryl-tetrazolen; ein duplikationsverfahren zur darstellung von polyarylen☆
TL;DR: In this article, it was shown that the thermolysis of 5-substituted-2-acyl-tetrazoles (I) at 60-110° leads to quantitative loss of nitrogen and formation of an Nacylnitrilimine (III) as a hypothetical intermediate.
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Ringöffnungen der Azole, IX: Synthese oligomerer 1.3.4‐Oxadiazolyl‐m‐phenyle
TL;DR: In this article, a synthese definierter polyaryle with alternierenden m-Phenylen-and 134-oxadiazolyl-mphenyle is defined, in abwechselnder Folge als Kettenverlangerung ausgefuhrt.