Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs
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Cites methods from "Synthesis of 53 tissue and cell lin..."
...We examined the cis-associations of the novel BMI, WCadjBMI or WHRadjBMI loci with the expression of nearby genes from various tissues by performing a look-up in a library of>100 published expression datasets, as described previously by Zhang et al [48]....
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...We examined the cis-associations of the novel BMI, WCadjBMI or WHRadjBMI loci with the expression of nearby genes from various tissues by performing a look-up in a library of>100 published expression datasets, as described previously by Zhang et al [48]....
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265 citations
References
12,142 citations
"Synthesis of 53 tissue and cell lin..." refers methods in this paper
...Data were retrieved using the biomaRt package [87], available through the Bioconductor repository [88]....
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"Synthesis of 53 tissue and cell lin..." refers methods in this paper
...However, BLAT analysis [49] revealed that the chr4 and chr7 transcripts map with 83....
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"Synthesis of 53 tissue and cell lin..." refers background in this paper
...Strong eQTLs are often highly correlated with markers of disease and quantitative traits at loci identified in GWAS [8-13], suggesting that these eQTLs account for a significant fraction of human phenotypic variability....
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