Synthesis of retrofractamide A
About: This article is published in Phytochemistry.The article was published on 1987-01-01. It has received 3 citations till now. The article focuses on the topics: Piper retrofractum & Piperaceae.
Citations
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TL;DR: Extraction of the stems and leaves of Piper ridleyi with ether afforded N - iso butyl-15-(3′,4′-methylenedioxyphenyl)-2 E,4 E,12 E -pentadecatrienamide (ridleyamide), as well as the known amide, retrofractamide, and sterols was described in this paper.
18 citations
TL;DR: Two natural piperamides and their derivatives were synthesized and evaluated for inhibitory activity against histone deacetylases, as well as the HCT-116 human colon cancer cell line.
9 citations
TL;DR: A total synthesis of guineensine, a secondary metabolite of the Piperaceae family, has been executed in 12 steps with an overall yield of 27% and featured novel application of a Julia–Kocienski olefination reaction which effectively constructed alkenamide skeleton.
9 citations
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TL;DR: In this article, two unsaturated amides, retrofractamides A and C, were isolated from the total aboveground parts of Piper retroractum and were shown to be N -isobutyl-9(3′,4′-methylenedioxyphenyl)2 E,4 E,8 E -nonatrienamide from spectroscopic and chemical investigations.
42 citations