Systematic review of randomised controlled trials of over the counter cough medicines for acute cough in adults.
Knut Schroeder,Tom Fahey +1 more
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TLDR
Over the counter cough medicines for acute cough cannot be recommended because there is no good evidence for their effectiveness and the effect sizes were small and of doubtful clinical relevance.Abstract:
Objectives To determine whether over the counter cough medicines are effective for acute cough in adults. Design Systematic review of randomised controlled trials.read more
Citations
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ERS guidelines on the assessment of cough
Alyn H. Morice,Giovanni A. Fontana,Maria G. Belvisi,Surinder S. Birring,Kian Fan Chung,Peter V. Dicpinigaitis,J A Kastelik,Lorcan McGarvey,Jaclyn A. Smith,Milos Tatar,John Widdicombe +10 more
TL;DR: Cough can have profound effects on health status, which can be assessed by cough-specific health status questionnaires, and may be used to follow change in cough reflex sensitivity in an individual.
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Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents.
Ian M. Paul,Jessica S. Beiler,Amyee McMonagle,Michele L. Shaffer,Laura M. Duda,Cheston M. Berlin +5 more
TL;DR: In a comparison of honey, DM, and no treatment, parents rated honey most favorably for symptomatic relief of their child's nocturnal cough and sleep difficulty due to upper respiratory tract infection.
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TRPA1 Agonists Evoke Coughing in Guinea Pig and Human Volunteers
Mark A. Birrell,Maria G. Belvisi,Megan S. Grace,Laura R. Sadofsky,Shoaib Faruqi,David J Hele,Sarah A. Maher,Véronique Freund-Michel,Alyn H. Morice +8 more
TL;DR: This study identifies the TRPA1 receptor as a promiscuous receptor, activated by a wide range of stimuli, making it a perfect target for triggering cough and as such one of the most promising targets currently identified for the development of antitussive drugs.
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Self-medication among children and adolescents in Germany: results of the National Health Survey for Children and Adolescents (KiGGS)
Yong Du,Hildtraud Knopf +1 more
TL;DR: Self-medication in younger children using such drugs as CCMs and aspirin suggested inappropriate drug use and potential risks, and should be closely monitored and warrants an education programme for parents in Germany.
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Treatment of the common cold.
TL;DR: Topical and oral nasal decongestants have been shown to relieve nasal symptoms and can be used in adolescents and adults for up to three days, and topical ipratropium, a prescription anticholinergic, relieves nasal symptoms in older children and adults.
References
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Journal ArticleDOI
Over-the-counter medications for acute cough in children and adults in ambulatory settings.
TL;DR: There is no good evidence for or against the effectiveness of OTC medicines in acute cough, with higher numbers of adverse effects in participants taking preparations containing antihistamines and dextromethorphan.
Journal ArticleDOI
Over-the-counter cold medications. A critical review of clinical trials between 1950 and 1991.
TL;DR: No good evidence has demonstrated the effectiveness of over-the-counter cold medications in preschool children, and further studies are required to clarify the role of these medications in children.
Journal ArticleDOI
Cough and the common cold
Frederick J. Curley,Richard S. Irwin,Melvin R. Pratter,Diane H. Stivers,Gary V. Doern,Paul A. Vernaglia,Andrew B. Larkin,Stephen P. Baker +7 more
TL;DR: It is concluded that the cough of the common cold arose from upper respiratory tract stimuli and that cough and other cardinal symptoms of thecommon cold were reduced with antihistamine-decongestant therapy when these symptoms were at their worst.
Journal ArticleDOI
Assessment of the antitussive efficacy of codeine in cough associated with common cold.
C Freestone,Ronald Eccles +1 more
TL;DR: The aims of this study were to study the antitussive efficacy of codeine in cough associated with URTI and to validate a sound meter as tool for quantifying cough.