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Open AccessJournal ArticleDOI

Systematic review of the adverse effects of cutaneous leishmaniasis treatment in the New World.

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TLDR
Although closer surveillance is needed for the treatment of cutaneous leishmaniasis, antileishmanial drugs are basically safe and severe side effects requiring the discontinuation of treatment are relatively uncommon.
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This article is published in Acta Tropica.The article was published on 2011-05-01 and is currently open access. It has received 306 citations till now. The article focuses on the topics: Adverse effect & Leishmaniasis.

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Journal ArticleDOI

Cutaneous and mucocutaneous leishmaniasis : Differential diagnosis, diagnosis, histopathology, and management

TL;DR: The diagnosis of leishmaniasis can be challenging because it mimics both infectious and malignant conditions as discussed by the authors, and a misdiagnosis may lead to an unfavorable outcome, and appropriate management requires an accurate diagnosis, which often includes identification of the specific etiologic species.
Journal ArticleDOI

Chemical composition of Mentha pulegium and Rosmarinus officinalis essential oils and their antileishmanial, antibacterial and antioxidant activities

TL;DR: Findings show that the EOs of M. pulegium and R. officinalis are good sources of bioactive molecules that could have potential applications in the food and pharmaceutical industries.

Oportunidades para inovação no tratamento da leishmaniose usando o potencial das plantas e produtos naturais como fontes de novos fármacos Potential for innovation in the treatment of leishmaniasis using plants and natural products as sources of new drugs

TL;DR: The main drug used in Brazil, Glucantime®, presents several adverse effects and represents high cost to the country as discussed by the authors, and the drugs of choice for all clinical forms of leishmaniasis are still pentavalent antimonials.
References
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Book

Cochrane Handbook for Systematic Reviews of Interventions

TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal ArticleDOI

The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and ElaborationPRISMA: Explanation and Elaboration

TL;DR: The updating of the QUOROM Statement is described, to ensure clear presentation of what was planned, done, and found in a systematic review, and the name of the reporting guidance was changed to PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses).
Book ChapterDOI

International Conference On Harmonisation Of Technical Requirements For Registration Of Pharmaceuticals For Human Use

John Abraham
TL;DR: The official goal of the ICH is to harmonize inconsistent technical regulatory standards across different regions and countries in order to avoid costly, wasteful, and duplicative testing in pharmaceutical development.
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