Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias — An Updated Review
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"Systematic Review of the Empirical ..." refers background or methods or result in this paper
...Easterbrook et al [24] found that compared with unfunded studies, government funded studies were more likely to yield statistically significant results but government sponsorship was not found to have a statistically significant effect on the likelihood of publication and company sponsored trials were less likely to be published or presented....
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...No information other than the study report was available for one empirical study [24] due to its age....
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...Status of approved protocols for Easterbrook 1991 study [24]....
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...Easterbrook et al [24] also found that study publication bias was greater with observational and laboratory-based experimental studies (Odds Ratio (OR) 3.79, 95% CI; 1.47, 9.76) than with RCTs (OR 0.84, 95% CI; 0.34, 2.09)....
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...Easterbrook et al [24] also found that study publication bias was greater with observational and laboratory-based experimental studies (Odds Ratio (OR) 3....
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2,601 citations
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Additional excerpts
...Several studies investigated a cohort of trials submitted to drug licensing authorities [38,40,41,65] and all found that many of these trials remain unpublished, with one study demonstrating that trials with positive outcomes resulted more often in submission of a final report to the regulatory authority [40]....
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1,876 citations
"Systematic Review of the Empirical ..." refers background in this paper
...While much effort has been invested in trying to identify the former [2], it is equally important to understand the nature and frequency of missing data from the latter level....
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...uk Introduction Study publication bias arises when studies are published or not depending on their results; it has received much attention [1,2]....
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1,638 citations
"Systematic Review of the Empirical ..." refers background or methods in this paper
...The main objective of the study by Blumle et al [31] was to consider how eligibility criteria stated in protocols was reported in subsequent reports, in doing so they noted that 52% of studies in their cohort were published, decreasing to 48% for RCTs only....
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...Four cohorts included only RCTs [17,18,25,29]; in the remaining cohort [26] the proportion of included RCTs was 13%....
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...Those studies containing exclusively nonRCTs were excluded....
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...Four of the empirical studies [17,25,26,29] assessed protocols approved by ethics committees and one empirical study [18] assessed those approved by a health institute....
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...Both cohorts containing exclusively RCTs or containing a mix of RCTs and non-RCTs were eligible....
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