Journal ArticleDOI
Technetium-99m DTPA: a new radiopharmaceutical for brain and kidney scanning.
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TLDR
Technetium 99m was combined with the chelating agent DTPA in order to obtain a scanning agent with the physical properties of the radionuclide technetium 98m and the desirable biological properties of che lating agents.Abstract:
Technetium 99m was combined with the chelating agent DTPA in order to obtain a scanning agent with the physical properties of the radionuclide technetium 99m and the desirable biological properties of chelating agents. The method for the preparation of the chelate is described. No toxic effects are expected. About 90 per cent of the compound is eliminated by the kidneys in twenty-four hours. The absorbed radiation dose is 0.042 rad/mCi by the kidneys and 0.555 rad/mCi by the bladder. In clinical studies the chelate is useful for scanning of brain and kidneys and for vascular dynamic studies.read more
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Journal ArticleDOI
Measurement of the distribution volume of gadopentetate dimeglumine at echo-planar MR imaging to quantify myocardial infarction: comparison with 99mTc-DTPA autoradiography in rats.
Håkan Arheden,Maythem Saeed,Charles B. Higgins,Dong-Wei Gao,Jens Bremerich,Rolf Wyttenbach,Michael W. Dae,Michael F. Wendland +7 more
TL;DR: The fractional distribution volumes of gadopentetate dimeglumine and 99mTc-DTPA are similar and indicate extracellular distribution in normal myocardium and intracellular as well as extrace cellular distribution in reperfused infarction.
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Utility of radioisotopic filtration markers in chronic renal insufficiency: simultaneous comparison of 125I-iothalamate, 169Yb-DTPA, 99mTc-DTPA, and inulin. The Modification of Diet in Renal Disease Study.
Ronald D. Perrone,Theodore I. Steinman,Gerald J. Beck,Christine Skibinski,Henry D. Royal,Maureen Lawlor,Lawrence G. Hunsicker +6 more
TL;DR: It is concluded that the renal clearance of 99m Tc-diethylenetriaminepentaacetic acid, 169 Yb-DTPA, or 125 I-iothalamate administered as a single IV or subcutaneous injection can be used to accurately measure GFR in subjects with renal insufficiency; use of the single injection technique may overestimate G FR in normal subjects.
Journal ArticleDOI
Left ventricular ejection fraction—A review of several radionuclide angiographic approaches using the scintillation camera
Journal ArticleDOI
Overview of transition metal and lanthanide complexes as diagnostic tools
L. Thunus,R. Lejeune +1 more
TL;DR: A review of magnetic resonance imaging contrast agents used in the study of several organ systems, including vascular structures, liver, spine and brain, heart, kidneys, skeleton, lungs and abdominal diseases is presented in this article.
Journal ArticleDOI
Medical Diagnostic Imaging with Complexes of 99mTc
Mike Clarke,Lisa Podbielski +1 more