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Journal Article

Terminalia Arjuna: Its Chemistry, Pharmacology and Therapeutic Action.

01 Feb 1929-Indian medical gazette (Calcutta School of Trop. Med. & Hyg., Calcutta.)-Vol. 64, Iss: 2, pp 70-73
About: This article is published in Indian medical gazette.The article was published on 1929-02-01 and is currently open access. It has received 12 citations till now. The article focuses on the topics: Terminalia arjuna.
Citations
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Journal ArticleDOI
TL;DR: Proposition to administer Terminalia arjuna along with statins deserves to be explored in depth for defining its place in the over all management and prevention of coronary artery disease.

223 citations

Journal ArticleDOI
TL;DR: It is suggested that Au NPs induces the mitotic cell division and pollen germination and there was no cytotoxic effect of Allium cepa root tip cells and Gloriosa superba pollen grains.

103 citations

Journal ArticleDOI
TL;DR: A rapid and sensitive analytical method was developed using reverse phase high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry for qualitative analysis to determine the array of bioactive phytochemicals and their variations in different plant parts.
Abstract: Terminalia arjuna is a medicinal plant used in ethnomedicine and the codified traditional medicine. A number of active constituents are reported, but there is no information on the whole range of gallic and ellagic acid derivatives present in this plant A rapid and sensitive analytical method was developed using reverse phase high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) for qualitative analysis to determine the array of bioactive phytochemicals and their variations in different plant parts viz. bark, unripe fruit, ripe fruit, leaf, root and stem. Separation was performed on a Thermo Betasil C8 column (250 mm x 4.5 mm, 5 µm) with a mobile phase consisted of 0.1% formic acid aqueous solution and acetonitrile at a flow rate of 0.5 mL/min in 55 min. A wide range of constituents of T. arjuna were characterized and broadly grouped as 27 gallic acid and 52 ellagic acid derivatives.

83 citations


Cites background from "Terminalia Arjuna: Its Chemistry, P..."

  • ..., family Combretaceae, is a wellknown ethno and traditional medicinal plant commonly known as Arjuna and found in sub-Himalayan regions of India, namely Uttar Pradesh, Bihar and mostly on the riversides of the Deccan region [1,2]....

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  • ...0166 was identified as the [M-H-CH3-CO2] and [M-H-C2H5-CO2] ion for compound 44 and 70, respectively [2]....

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Journal ArticleDOI
TL;DR: Withania somnifera may therefore be useful for generalized weakness and to improve speed and lower limb muscular strength and neuro-muscular co-ordination and both drugs appear to be safe for young adults when given for mentioned dosage and duration.
Abstract: Introduction Several medicinal plants have been described to be beneficial for cardiac ailments in Ayurveda like Ashwagandha and Arjuna. Ashwagandha-categorised as Rasayanas, and described to promote health and longevity and Arjuna primarily for heart ailments. coronary artery disease, heart failure, hypercholesterolemia, anginal pain and can be considered as a useful drug for coronary artery disease, hypertension and ischemic cardiomyopathy. Objective There are no scientific clinical studies showing effect of both these drugs on exercise performance after regular administration when given as supplements The present study was therefore designed and performed to assess the effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) individually and as a combination on maximum velocity, average absolute and relative Power, balance, maximum oxygen consumption (VO2 max) and blood pressure in humans. Materials and methods Forty normal healthy. Subjects (either sex, mean age 20.6 ± 2.5yrs and mean Body Mass Index 21.9 ± 2.2) were recruited after written informed consent was obtained. Institutional Ethics Committee permission was also obtained. Thirty participants were assigned to experimental group of which 10 received standardized root extracts of Withania somnifera, 10 received standardized bark extract of Terminalia arjuna and the rest of the 10 received standardized root extract of Withania somnifera in addition to bark extract of Terminalia arjuna both. Both the drugs were given in the form of capsules (dosage 500mg/day for both the drugs). Ten participants received placebo (capsules filled with flour). All the subjects continued the regimen for 8 weeks. All variables were assessed before and after the course of drug administration Observations Our study showed that Withania somnifera increased velocity, power and VO2 max whereas Terminalia arjuna increased VO2 max and lowered resting systolic blood pressure. When given in combination, the improvement was seen in all parameters except balance and diastolic blood pressure. Conclusion Withania somnifera may therefore be useful for generalized weakness and to improve speed and lower limb muscular strength and neuro-muscular co-ordination. Terminalia arjuna may prove useful to improve cardio-vascular endurance and lowering systolic blood pressure. Both drugs appear to be safe for young adults when given for mentioned dosage and duration.

67 citations


Cites background from "Terminalia Arjuna: Its Chemistry, P..."

  • ...ground level and belongs to the Combretaceae family.[8,9] It is described as an alexteric, stryptic, tonic, and anthelmintic agent and is also useful in treatment of fractures, ulcers, heart diseases, biliousness, urinary discharges, asthma, tumours, leucoderma, anaemia, excessive perspiration[8] etc and its bark is useful in the treatment of coronary artery disease, heart failure, hypercholesterolemia, anginal pain[10] and can be considered as a useful drug for coronary artery disease, hypertension and ischemic cardiomyopathy....

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  • ...[8,9] It is described as an alexteric, stryptic, tonic, and anthelmintic agent and is also useful in treatment of fractures, ulcers, heart diseases, biliousness, urinary discharges, asthma, tumours, leucoderma, anaemia, excessive perspiration[8] etc and its bark is useful in the treatment of coronary artery disease, heart failure, hypercholesterolemia, anginal pain[10] and can be considered as a useful drug for coronary artery disease, hypertension and ischemic cardiomyopathy....

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Journal ArticleDOI
TL;DR: In this article, a comparative profiling of phenolic constituents in different plant parts of six Terminalia species namely T. arjuna, T. bellerica and T. paniculata using ultra-performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry (UPLC-QqQLIT-MS/MS).

31 citations

References
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01 Jan 1909

2 citations