TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.
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...Classically, effector CD4 + T cells have been assigned to the T helper type 1 (T H 1) or T H 2 lineage based on their cytokine profile...
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Cites background from "TH1 and TH2 cells: different patter..."
...Effector T H cells have been classified as type 1 (T H 1) and type 2 (T H 2) based on their cytokine expression profiles and immune regulatory functio...
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References
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"TH1 and TH2 cells: different patter..." refers background or methods in this paper
...clones expressed relatively more ppENK (11)....
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...Conversely, only TH2 clones synthesize detectable amounts of IL-4, IL-5 (11), and probably IL-6 (F....
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...Using monoclonal ntibodies that neutralize the biological activities of IL-2 (6) and IL-4 (9), these bioassays can be monospecific for either lymphokine (11)....
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...kines and other secreted proteins (11)....
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...n_g periods in culture, while the synthesis of other lymphokines appears to be more stable (11)....
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"TH1 and TH2 cells: different patter..." refers background in this paper
...The T-cell population was further divided when surface markers allowed separation of helper cells from cytotoxic cells (3)....
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