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Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli.

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TLDR
Patagonia's biodiversity has been explored from many points of view, however, skin secretions of native amphibians have not been evaluated for antimicrobial peptide research until now and the first peptides described for amphibians of the Pleurodema genus are described.
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This article is published in Gene.The article was published on 2017-03-20 and is currently open access. It has received 21 citations till now. The article focuses on the topics: Antimicrobial peptides & Pleurodema.

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Citations
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Exploring Molecular-Biomembrane Interactions with Surface Plasmon Resonance and Dual Polarization Interferometry Technology: Expanding the Spotlight onto Biomembrane Structure

TL;DR: A review of the application of surface plasmon resonance and dual polarization interferometry-based biosensors to the study of biomembrane-based systems using both planar mono- or bilayers or liposomes is presented.
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Synergistic and antibiofilm properties of ocellatin peptides against multidrug-resistant Pseudomonas aeruginosa.

TL;DR: Ocellatin-PT3 may be promising as a template for the development of novel antimicrobial peptides against P. aeruginosa, and was capable of preventing the proliferation of 48-h mature biofilms at concentrations ranging from 4 to 8× the MIC.
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Biological properties of chitosan derivatives associated with the ceftazidime drug.

TL;DR: The biocompatibility of the derivatives was confirmed by the low hemolytic rate (<5%), non-toxic on Artemia salina (LD50%>3000 ppm), and significant index (1-34%) of antioxidant activity, and the results demonstrated that chitosan and its derivatives are promising biomaterials.
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An Atlas of Anionic Antimicrobial Peptides from Amphibians.

TL;DR: It is concluded that amphibian AAMPs represent an untapped potential source of biologically active agents and merit far greater research interest.
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Bioinspired Designs, Molecular Premise and Tools for Evaluating the Ecological Importance of Antimicrobial Peptides

TL;DR: An overview of recent developments in antimicrobial peptides (AMPs), summarizing structural diversity, potential new applications, activity targets and microbial killing responses in general is provided.
References
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Journal ArticleDOI

AntiBP2: improved version of antibacterial peptide prediction

TL;DR: Among antibacterial peptides, there is preference for certain residues at N and C terminus, which helps to discriminate them from non-antibacterial peptide and their further classification in source and family is studied.
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Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.

TL;DR: Two groups of antimicrobial peptides have been isolated from skin secretions of Bombina maxima with potent antimicrobial activity, cytotoxicity against tumor cells and spermicidal action of maximins, and maximin 3 possessed a significant anti-HIV activity.
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Host-defence peptides from the glandular secretions of amphibians: structure and activity

TL;DR: This review covers the literature on the subject of biologically active peptide from the glands of amphibians, which include neuropeptides, antimicrobial and anticancer active peptides, antiviral agents, fungicides and peptides which complex with Ca2+ calmodulin.
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Temporins, Small Antimicrobial Peptides with Leishmanicidal Activity

TL;DR: The unique properties of temporins, as well as their membranolytic effect, which should make it difficult for the pathogen to develop resistance, suggest them as potential candidates for the future design of antiparasitic drugs with a new mode of action.
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MSI-99, a magainin analogue, imparts enhanced disease resistance in transgenic tobacco and banana.

TL;DR: The results suggest that MSI-99 can be useful in imparting enhanced disease resistance in transgenic plants and tobacco plants transformed with pMSI168 showed enhanced resistance against Sclerotinia sclerotiorum, Alternaria alternata and Botrytis cinerea.
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Q1. What contributions have the authors mentioned in the paper "Thaulin-1: the first antimicrobial peptide isolated from the skin of a patagonian frog pleurodema thaul (anura: leptodactylidae: leiuperinae) with activity against escherichia coli" ?

Please cite this article as: Mariela M. Marani, Luis O. Perez, Alyne Rodrigues de Araujo, Alexandra Plácido, Carla F. Sousa, Patrick Veras Quelemes, Mayara Oliveira, Ana G. Gomes-Alves, Mariana Pueta, Paula Gameiro, Ana M. Tomás, Cristina Delerue-Matos, Peter Eaton, Silvia A. Camperi, Néstor G. Basso, Jose Roberto de Souza de Almeida Leite, Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul ( Anura: Leptodactylidae: Leiuperinae ) with activity against Escherichia coli. The address for the corresponding author was captured as affiliation for all authors. 

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