The Added Role of MR Imaging in Treatment Stratification of Patients with Gynecologic Malignancies: What the Radiologist Needs to Know
Citations
138 citations
Cites background from "The Added Role of MR Imaging in Tre..."
...2% of cases) it may result from a sarcomatous transformation in a benign leiomyoma (2)....
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...Some authors have suggested the presence of irregular margins, necrosis, and rapid growth as the most suggestive features of malignancy (2)....
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...U terine sarcomas are a rare heterogeneous group of tumors of mesenchymal origin, accounting for approximately 8% of uterine malignancies (1), although they were thought to represent only 2% to 3% of all uterine tumors in the past (2)....
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125 citations
111 citations
Cites methods from "The Added Role of MR Imaging in Tre..."
...Diffusion-weighted (DW) imaging is increasingly used as an add-on to T2 and DCE MR imaging [15, 16], even if DW imaging is not yet included in current imaging guidelines updated by 2011 [9, 12]....
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96 citations
Cites background from "The Added Role of MR Imaging in Tre..."
...Furthermore, whole-body staging is important, especially in advanced gynaecological cancer, in which incidence of extrapelvic disease at time of diagnosis is high [15]....
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...The presence of lymph node metastases represents generally a poor prognostic factor and is partly influential on therapy planning, especially in cervical and endometrial cancers [14, 15, 30]....
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93 citations
Cites background or methods from "The Added Role of MR Imaging in Tre..."
...MRI has no role in evaluating stage IA cervical cancer, because microscopic disease cannot be reliably detected [20]....
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...Parametrial extension can be overestimated on T2weighted images, especially in large tumours, which can induce changes in the surrounding stromal tissue due to tumour compression or increased inflammation [20, 41]....
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...Especially in cases of advanced disease, PET/CT has a high sensitivity (75-100%) and specificity (87-100%) [20] and can help demonstrate sites of unexpected disease such as supraclavicular lymph nodes [72]....
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...Where available, conventional MRI is the preferred imaging modality for evaluating the local extent of cervical cancer due to its excellent soft tissue contrast [20, 21]....
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...MRI can accurately exclude parametrial invasion, with a negative predictive value ranging from 94–100% [20, 36]....
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References
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