Open AccessJournal Article
The assessment of skeletal maturity in the growing rat.
P C Hughes,J M Tanner +1 more
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This article is published in Journal of Anatomy.The article was published on 1970-03-01 and is currently open access. It has received 112 citations till now. The article focuses on the topics: Metacarpus & Humerus.read more
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A simple disc degeneration model induced by percutaneous needle puncture in the rat tail.
TL;DR: Tail disc percutaneous needle punctures is a simple method for inducing disc degeneration and the rate of degeneration is positively related to the depth of needle puncture, which should be taken into consideration when results of disc regeneration research in this model are interpreted and extrapolated to human.
Journal ArticleDOI
Relation between Age of Onset of Obesity and Size and Number of Adipose Cells
TL;DR: The size and number of adipose cells in obese children and adults were compared with control data and an increase in adipose cell size was found in all the obese subjects.
Journal ArticleDOI
ISSLS prize winner: repeated disc injury causes persistent inflammation.
TL;DR: The results demonstrate that repeated injury during active healing leads to persistent inflammation and enhanced disc degeneration, and support the premise that damage accumulation and its associated inflammation may distinguish pathologic from physiologic disc degenerations.
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Expression of Indian hedgehog, parathyroid hormone-related protein, and their receptors in the postnatal growth plate of the rat: evidence for a locally acting growth restraining feedback loop after birth.
Bram C. J. van der Eerden,Marcel Karperien,Evelien F. Gevers,Clemens W.G.M. Löwik,Jan M. Wit +4 more
TL;DR: In this article, a locally acting growth restraining feedback loop has been identified in the murine embryonic growth plate in which the level of parathyroid hormone-related peptide (PTHrP) expression regulates the pace of chondrocyte differentiation.
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Stab incision for inducing intervertebral disc degeneration in the rat.
Marc-Antoine Rousseau,Jill A. Ulrich,Elisa C. Bass,Azucena G. Rodriguez,Jane Liu,Jeffrey C. Lotz +5 more
TL;DR: Tail disc stab injury was successful in creating morphologic signs of degeneration and transient high concentrations of IL-1β, however, the degenerative response in the lumbar discs was much slower, suggesting that site-specific factors, such as increased stability due to posterior elements and torso musculature, helped facilitate healing.
References
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Journal ArticleDOI
Body weight and food intake as initiating factors for puberty in the rat
G. C. Kennedy,J. Mitra +1 more
Journal Article
A longitudinal study of the growth of the black-hooded rat: methods of measurement and rates of growth for skull, limbs, pelvis, nose-rump and tail lengths.
P C Hughes,J M Tanner +1 more
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Effects of the pituitary growth hormone and of thyroxin on growth and differentiation of the skeleton of the rat thyroidectomized at birth
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Some effects of accelerating growth. II. Skeletal development.
TL;DR: Rapidly growing animals of the same body weight as their slow growing litter-mates, but younger in age, had femora which were shorter and contained less calcium, and their epiphy-seal development was not so far advanced.
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Intervertebral disc cell death is dependent on the magnitude and duration of spinal loading.
Jeffrey C. Lotz,Jennie R. Chin +1 more