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Open AccessJournal ArticleDOI

The behaviour of chromatolysed motoneurones studied by intracellular recording.

J. C. Eccles, +2 more
- 29 Aug 1958 - 
- Vol. 143, Iss: 1, pp 11-40
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This article is published in The Journal of Physiology.The article was published on 1958-08-29 and is currently open access. It has received 317 citations till now. The article focuses on the topics: Intracellular.

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Journal ArticleDOI

Electrophysiological properties of in vitro purkinje cell dendrites in mammalian cerebellar slices

TL;DR: Intradendritic recordings from Purkinje cells in vitro indicate that white matter stimulation produces large synaptic responses by the activation of the climbing fibre afferent, but antidromic potentials do not actively invade the dendritic tree.
Book ChapterDOI

The Axon Reaction: A Review of the Principal Features of Perikaryal Responses to Axon Injury

TL;DR: This chapter provides an overview of the principal features of perikaryal responses to axon injury and changes in axotomized neurons are generally assessed by comparison with the corresponding contralateral neurons of the experimental animal.
Journal ArticleDOI

Neural plasticity after peripheral nerve injury and regeneration.

TL;DR: An important direction for ongoing research is the development of therapeutic strategies that enhance axonal regeneration, promote selective target reinnervation, but are also able to modulate central nervous system reorganization, amplifying those positive adaptive changes that help to improve functional recovery but also diminishing undesirable consequences.
References
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Journal ArticleDOI

A quantitative description of membrane current and its application to conduction and excitation in nerve

TL;DR: This article concludes a series of papers concerned with the flow of electric current through the surface membrane of a giant nerve fibre by putting them into mathematical form and showing that they will account for conduction and excitation in quantitative terms.
Journal ArticleDOI

The ionic basis of electrical activity in nerve and muscle

A. L. Hodgkin
- 01 Nov 1951 - 
TL;DR: This hypothesis is applied to the phenomena of subthreshold activity, accomodation and oscillatory behaviour and it is suggested that both permeability changes vary with membrane potential in a graded but reversible manner.
Journal ArticleDOI

The effect of internal and external potassium concentration on the membrane potential of frog muscle.

TL;DR: The present paper describes experiments in which the membrane potential of frog sartorius muscle was measured in solutions of different potassium content, and in solutions which were designed to alter the inside concentration of potassium keeping the outside concentration constant.
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