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Journal ArticleDOI

The Chemistry and Properties of the Medical-Grade Silicones

Silas Braley1
01 May 1970-Journal of Macromolecular Science, Part A (Taylor & Francis Group)-Vol. 4, Iss: 3, pp 529-544
TL;DR: In this article, the chemistry of these materials from the original polymer manufacturing through the various stages necessary to obtain the types of heat vulcanizing silicone rubber, room temperature vulcanising silicone rubber and silicone rubber adhesive most commonly used in medical applications.
Abstract: The medical grade silicones are probably the most widely used of all the synthetic polymers for permanently implanted subdermal devices. This paper reviews the chemistry of these materials from the original polymer manufacturing through the various stages necessary to obtain the types of heat vulcanizing silicone rubber, room temperature vulcanizing silicone rubber, and silicone rubber adhesive most commonly used in medical applications.
Citations
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Journal ArticleDOI
TL;DR: In this paper, the morphology, wettability and surface chemical characteristics of polydimethylsiloxane (PDMS) surfaces have been investigated by performing scanning electron microscopy (SEM) and attenuated total reflectance infrared (ATR-FTIR) spectroscopy.

264 citations

Journal ArticleDOI
TL;DR: This review summarizes studies on effects of silicon and silica nano- and micro-particles on cells and organs following four main exposure routes, namely, intravenous, pulmonary, dermal and oral, and concludes with an outlook on improving and standardizing biocompatibility assessment.

209 citations


Cites background from "The Chemistry and Properties of the..."

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  • ...As an example, Si and SiO based materials are used for decades in dietary supplements[4], bandages[5], catheters and implants[5], dental fillers[6] and contact lenses[5]....

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Journal ArticleDOI
TL;DR: Elastomers will find increasing use in medical products, offering biocompatibility, durability, design flexibility, and favorable performance/cost ratios.
Abstract: Current topics in elastomers for biomedical applications are reviewed. Elastomeric biomaterials, such as silicones, thermoplastic elastomers, polyolefin and polydiene elastomers, poly(vinyl chloride), natural rubber, heparinized polymers, hydrogels, polypeptides elastomers and others are described. In addition biomedical applications, such as cardiovascular devices, prosthetic devices, general medical care products, transdermal therapeutic systems, orthodontics, and ophthalmology are reviewed as well. Elastomers will find increasing use in medical products, offering biocompatibility, durability, design flexibility, and favorable performance/cost ratios. Elastomers will play a key role in medical technology of the future.

189 citations

Journal ArticleDOI
TL;DR: In this paper, a hybrid system that combines material jetting and material extrusion was introduced to increase the fabrication velocity between 10 to 20 times compared to the regular extrusion methods.

78 citations

References
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Book
01 Jan 1968
Abstract: Bargaining with reading habit is no need. Reading is not kind of something sold that you can take or not. It is a thing that will change your life to life better. It is the thing that will give you many things around the world and this universe, in the real world and here after. As what will be given by this chemistry and technology of silicones, how can you bargain with the thing that has many benefits for you?

1,681 citations

Book
17 Aug 2013

53 citations