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The comorbidity of insomnia, chronic pain, and depression: dopamine as a putative mechanism.

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TLDR
It is argued that studies aiming to elucidate common factors accounting for the comorbidity of insomnia, chronic pain, and depression should evaluate functioning within the mesolimbic dopaminergic system and its effect on common processes known to be dysregulated in all three disorders.
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This article is published in Sleep Medicine Reviews.The article was published on 2013-06-01 and is currently open access. It has received 252 citations till now. The article focuses on the topics: Chronic pain & Dopaminergic.

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The association of sleep and pain: an update and a path forward

TL;DR: A critical review of the recent prospective and experimental research on the association of sleep and pain tries to identify trends suggestive of directionality and potential mechanisms to guide future clinical efforts to develop and augment treatments for chronic sleep disturbance and chronic pain.
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Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews.

TL;DR: The quality of evidence was low due to participant numbers, length of intervention and follow‐up, and the evidence for any adverse effects or harm associated with physical activity and exercise interventions, though even these statistically significant results had only small‐to‐moderate effect sizes.
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Assessment of Psychosocial and Functional Impact of Chronic Pain.

TL;DR: A set of key psychosocial and behavioral factors that should be considered when classifying patients within the comprehensive classification of chronic pain disorders developed by the AAPT are outlined and examples of assessment methods for each are described.
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Common Brain Mechanisms of Chronic Pain and Addiction

TL;DR: It is proposed that similar neuroadaptations exist in chronic pain patients that have been attributed to reward deficiency, impaired inhibitory control, incentive sensitization, aberrant learning, and anti-reward allostatic neuroadaptation.
References
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Journal ArticleDOI

Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study

TL;DR: For example, this article found a strong relationship between the breadth of exposure to abuse or household dysfunction during childhood and multiple risk factors for several of the leading causes of death in adults.
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Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: The BIS/BAS Scales

TL;DR: In this paper, self-report scales to assess dispositional BIS and behavioral activation system (BAS) sensitivities were created, and a situation in which Ss anticipated a punishment was created.
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Risk and protective factors for alcohol and other drug problems in adolescence and early adulthood: Implications for substance abuse prevention.

TL;DR: The authors suggest that the most promising route to effective strategies for the prevention of adolescent alcohol and other drug problems is through a risk-focused approach.
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Epidemiology of insomnia: what we know and what we still need to learn

TL;DR: The association between insomnia and major depressive episodes has been constantly reported: individuals with insomnia are more likely to have a major depressive illness and longitudinal studies have shown that the persistence of insomnia is associated with the appearance of a new depressive episode.
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Depression and pain comorbidity: a literature review.

TL;DR: A model that incorporates assessment and treatment of depression and pain simultaneously is necessary for improved outcomes.
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