Journal ArticleDOI
The cut-off values for the intima-media complex thickness assessed by colour Doppler sonography in seven cranial and aortic arch arteries.
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TLDR
The involvement of a large array of arteries is easily and commonly detected by CDS and provides a high diagnostic yield in patients with suspected GCA, and proposed IMT cut-off values might further improve the diagnostic utility of CDS in these patients.Abstract:
Objectives Colour Doppler sonography (CDS) is becoming ever more important in the diagnosis of GCA. Data on cut-off values for intima-media complex thickness (IMT) that can be used in clinical practice to distinguish between normal and inflamed arteries are limited. We aimed to derive potential cut-off values for IMT of seven preselected arteries by comparing IMT between GCA patients and a control group. Methods We performed CDS of the preselected temporal, facial, occipital, carotid, vertebral, subclavian and axillary arteries in consecutive newly diagnosed GCA patients between October 2013 and September 2019. A 'halo' with positive compression sign was considered a positive finding. We measured the maximum IMT in the preselected arteries and compared it with the maximum IMT of the control group. Results We were able to demonstrate a halo sign in at least one of the examined arteries of 244/248 (98.4%) GCA patients. Temporal arteries were the most commonly affected vessels, involved in 192 (77.4%) patients. We found extracranial large vessel involvement in 87 (35.1%) patients. The following cut-off values showed high levels of diagnostic accuracy: ≥0.4 mm for temporal, facial and occipital arteries, ≥0.7 mm for vertebral arteries, and ≥1 mm for carotid, subclavian and axillary arteries. Conclusion The involvement of a large array of arteries is easily and commonly detected by CDS and provides a high diagnostic yield in patients with suspected GCA. Proposed IMT cut-off values might further improve the diagnostic utility of CDS in these patients.read more
Citations
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Journal ArticleDOI
Ultrasound halo sign as a potential monitoring tool for patients with giant cell arteritis: a prospective analysis.
Cristina Ponte,Sara Monti,Carlo Alberto Scirè,Paolo Delvino,Nikita Khmelinskii,Alessandra Milanesi,Vitor H. Teixeira,Fabio Brandolino,Fernando Saraiva,Carlomaurizio Montecucco,João Eurico Fonseca,Wolfgang A. Schmidt,Raashid Luqmani +12 more
TL;DR: Ultrasound is a reliable imaging tool to assess disease activity and response to treatment in patients with GCA and should be evaluated direct treatment effect on halo features as an outcome measure of interest.
Journal ArticleDOI
Quantitative ultrasound to monitor the vascular response to tocilizumab in giant cell arteritis.
Luca Seitz,Lisa Christ,Fabian Lötscher,Godehard Scholz,Adela-Cristina Sarbu,Lukas Bütikofer,Florian Kollert,Wolfgang A. Schmidt,Stephan Reichenbach,Peter M. Villiger +9 more
TL;DR: In this paper, the effect of ultra-short glucocorticoids followed by Tocilizumab monotherapy on the intima-media thickness (IMT) in GCA patients was characterized.
Journal ArticleDOI
Extended ultrasound examination identifies more large vessel involvement in patients with giant cell arteritis.
Anne Bull Haaversen,Lene Kristin Brekke,Tanaz A. Kermani,Øyvind Molberg,Andreas P. Diamantopoulos +4 more
TL;DR: Extended A2-ultrasound examination, identified more patients with LV involvement than limited ultrasound method, but requires high expertise and high-end equipment and should be performed by ultrasonographers with adequate training.
Journal ArticleDOI
Diagnosing giant cell arteritis: a comprehensive practical guide for the practicing rheumatologist
Peter M Andel,Stavros Chrysidis,Julia Geiger,Anne Bull Haaversen,Glenn Haugeberg,Glenn Haugeberg,G. Myklebust,Berit Dalsgaard Nielsen,A. Diamantopoulos +8 more
TL;DR: In this paper, a simple algorithm for diagnosing GCA for use by rheumatologists not working in specialist centres is proposed, based on a review of the current evidence on GCA diagnostics.
Journal ArticleDOI
The provisional OMERACT ultrasonography score for giant cell arteritis
Christian Dejaco,Cristina Ponte,Sara Monti,Davide Rozza,Carlo Alberto Scirè,Lene Terslev,George A W Bruyn,Dennis Boumans,Wolfgang Hartung,Alojzija Hočevar,Marcin Milchert,Uffe Møller Døhn,Chetan Mukhtyar,Markus Aschwanden,Philipp Bosch,Dario Camellino,Stavros Chrysidis,Giovanni Ciancio,Maria Antonietta D'Agostino,Thomas Daikeler,Bhaskar Dasgupta,Eugenio de Miguel,Andreas P. Diamantopoulos,Christina Duftner,Ana Filipa Águeda,Ulrich Fredberg,Petra Hanova,Ib Tønder Hansen,Ellen Margrethe Hauge,Annamaria Iagnocco,Nevsun Inanc,Aaron Juche,Rositsa Karalilova,T. Kawamoto,Kresten Krarup Keller,Helen Keen,Tanaz A. Kermani,Minna J. Kohler,Matthew J. Koster,Raashid Luqmani,Pierluigi Macchioni,Sarah L. Mackie,Esperanza Naredo,Berit Dalsgaard Nielsen,H Ogasawara,Carlos Pineda,Valentin S. Schäfer,Luca Seitz,Alessandro Tomelleri,Karina D. Torralba,Kornelis S M van der Geest,Kenneth J. Warrington,Wolfgang A. Schmidt +52 more
TL;DR: In this article , the authors developed an Outcome Measures in Rheumatology (OMERACT) ultrasonography score for monitoring disease activity in giant cell arteritis (GCA) and evaluate its metric properties.
References
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Journal ArticleDOI
2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides
John Charles Jennette,Ronald Falk,P. A. Bacon,Neil Basu,Maria C. Cid,Franco Ferrario,Luis Felipe Flores-Suárez,W. L. Gross,Loïc Guillevin,E. C. Hagen,Gary S. Hoffman,David Jayne,Cees G. M. Kallenberg,Peter Lamprecht,Carol A. Langford,Raashid Luqmani,Alfred Mahr,Eric L. Matteson,Peter A. Merkel,Peter A. Merkel,Seza Ozen,Charles D. Pusey,Niels Rasmussen,Andrew J. Rees,David G. I. Scott,Ulrich Specks,John H. Stone,Kei Takahashi,Richard A. Watts +28 more
TL;DR: 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides J. Watts; Arthritis & Rheumatism
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John Charles Jennette,Ronald Falk,Neil Basu,Maria C. Cid,Franco Ferrario,Luis Felipe Flores-Suárez,W. L. Gross,Loïc Guillevin,E. C. Hagen,Peter Lamprecht,Raashid Luqmani,Seza Ozen,Andrew J. Rees,Scott Dgi,Ulrich Specks,Kei Takahashi,Richard A. Watts +16 more
TL;DR: In this article, the running head is assigned to one of the following candidates:Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F, Ferrardo F, Flores-Suarez LF, Gross WL, Guillevin L, Hagen EC, Hoffman GS, Jayne DR, Kallenberg CGM, Lamprecht P, Langford CA, Luqmani RA, Mahr AD, Matteson EL, Merkel PA, Ozen S, Pusey CD, Rasmussen N, Rees
Journal ArticleDOI
EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice.
Christian Dejaco,Sofia Ramiro,Christina Duftner,Florent L. Besson,Thorsten A. Bley,Daniel Engelbert Blockmans,Elisabeth Brouwer,Marco A. Cimmino,Eric Clark,Bhaskar Dasgupta,Bhaskar Dasgupta,Andreas P. Diamantopoulos,Haner Direskeneli,Annamaria Iagnocco,Thorsten Klink,Lorna Neill,Cristina Ponte,Carlo Salvarani,Riemer H. J. A. Slart,Madeline Whitlock,Wolfgang A. Schmidt +20 more
TL;DR: The task force recommends an early imaging test in patients with suspected LVV, with ultrasound and MRI being the first choices in GCA and TAK, respectively, which are the first EULAR recommendations providing up-to-date guidance for the role of imaging in the diagnosis and monitoring of patients with (suspected) LVV.
Journal ArticleDOI
The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis (TABUL): a diagnostic accuracy and cost-effectiveness study.
Raashid Luqmani,Ellen Lee,Surjeet Singh,M Gillett,Wolfgang A. Schmidt,Mike Bradburn,Bhaskar Dasgupta,Andreas P. Diamantopoulos,Wulf Forrester-Barker,William Hamilton,Shauna Masters,Brendan McDonald,Eugene McNally,Colin T. Pease,Jennifer Piper,John F Salmon,Allan Wailoo,Konrad Wolfe,Andrew Hutchings +18 more
TL;DR: The feasibility of providing training in ultrasound for the diagnosis of giant cell arteritis has been demonstrated and the results indicate better sensitivity but poorer specificity of ultrasound compared with biopsy and suggest some scope for reducing the role of biopsy.
Journal ArticleDOI
The fast-track ultrasound clinic for early diagnosis of giant cell arteritis significantly reduces permanent visual impairment: towards a more effective strategy to improve clinical outcome in giant cell arteritis?
TL;DR: The implementation of the FTC in GCA care appears to significantly reduce the risk of permanent visual impairment and is more cost effective by reducing the need for inpatient care.
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