The Default Mode Network in Autism
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TLDR
It is suggested that aberrancies in key nodes of the DMN and their dynamic functional interactions contribute to atypical integration of information about the self in relation to 'other', as well as impairments in the ability to flexibly attend to socially relevant stimuli.About:
This article is published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.The article was published on 2017-09-01 and is currently open access. It has received 235 citations till now. The article focuses on the topics: Theory of mind & Autism.read more
Citations
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The cingulum bundle: anatomy, function, and dysfunction
TL;DR: The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus, and non‐invasive imaging implicates it in executive control, emotion, pain, and episodic memory.
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Meditation leads to reduced default mode network activity beyond an active task
Kathleen A. Garrison,Thomas A. Zeffiro,Dustin Scheinost,R. Todd Constable,Judson A. Brewer,Judson A. Brewer +5 more
TL;DR: The results indicated that meditation is associated with reduced activations in the default mode network, relative to an active task, for meditators as compared to controls, and suggest that meditation leads to relatively reduced default mode processing beyond that observed during another active cognitive task.
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Individual variation in intentionality in the mind-wandering state is reflected in the integration of the default-mode, fronto-parietal, and limbic networks
Johannes Golchert,Jonathan Smallwood,Elizabeth Jefferies,Paul Seli,Julia M. Huntenburg,Franziskus Liem,Mark E. Lauckner,Sabine Oligschläger,Boris C. Bernhardt,Arno Villringer,Daniel S. Margulies +10 more
TL;DR: One reason why mind‐wandering has a controversial relationship with control is because it depends on whether the thoughts emerge in a deliberate or spontaneous fashion, which may depend upon integration between the default‐mode and fronto‐parietal networks.
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Genetic mapping and evolutionary analysis of human-expanded cognitive networks
Yongbin Wei,Siemon C. de Lange,Lianne H. Scholtens,Kyoko Watanabe,Dirk Jan Ardesch,Philip R. Jansen,Philip R. Jansen,Jeanne E. Savage,Longchuan Li,Todd M. Preuss,Todd M. Preuss,James K. Rilling,Danielle Posthuma,Martijn P. van den Heuvel +13 more
TL;DR: The authors show that genes highly divergent between humans and other primates (HAR genes) are particularly expressed in these brain regions, including elements of the central cognitive default mode network (DMN).
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Revisiting the Functional Anatomy of the Human Brain: Toward a Meta-Networking Theory of Cerebral Functions.
Guillaume Herbet,Hugues Duffau +1 more
TL;DR: This work challenges the traditional, outdated localisionnist view of brain processing, and proposes an alternative meta-networking theory that underlies the uniquely human propensity to learn complex abilities, and explains how postlesional reshaping can lead to some degrees of functional compensation in brain-damaged patients.
References
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A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
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Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control
William W. Seeley,Vinod Menon,Alan F. Schatzberg,Jennifer Keller,Gary H. Glover,Heather A. Kenna,Allan L. Reiss,Michael D. Greicius +7 more
TL;DR: Two distinct networks typically coactivated during functional MRI tasks are identified, anchored by dorsal anterior cingulate and orbital frontoinsular cortices with robust connectivity to subcortical and limbic structures, and an “executive-control network” that links dorsolateral frontal and parietal neocortices.
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Does the autistic child have a theory of mind
TL;DR: A new model of metarepresentational development is used to predict a cognitive deficit which could explain a crucial component of the social impairment in childhood autism.