Journal ArticleDOI
The discovery of a potent pure chemical wound-healing accelerator
Reads0
Chats0
About:
This article is published in American Journal of Surgery.The article was published on 1970-05-01. It has received 176 citations till now.read more
Citations
More filters
Journal ArticleDOI
Topical formulations and wound healing applications of chitosan.
TL;DR: Chitosan enhances the functions of inflammatory cells such as polymorphonuclear leukocytes (PMN), phagocytosis, production of osteopontin and leukotriene B4, macrophages, and fibroblasts, which promotes granulation and organization, therefore chitosans is beneficial for the large open wounds of animals.
Journal ArticleDOI
Evaluation of the biocompatibility of a chitosan scaffold in mice.
Pamela J. VandeVord,Howard W. T. Matthew,Stephen P. DeSilva,Lois Mayton,Bin Wu,Paul H. Wooley +5 more
TL;DR: It is suggested that chitosan may be suitable for the development of implantable materials after a preliminary study showed a high degree of biocompatibility in this animal model.
Journal ArticleDOI
Photocrosslinkable chitosan as a dressing for wound occlusion and accelerator in healing process
Masayuki Ishihara,Kuniaki Nakanishi,Katsuaki Ono,Masato Sato,Makoto Kikuchi,Yoshio Saito,Hirofumi Yura,Takemi Matsui,Hidemi Hattori,Maki Uenoyama,Akira Kurita +10 more
TL;DR: The chitosan hydrogel due to its accelerating healing ability is considered to become an excellent dressing for wound occlusion and tissue adhesive in urgent hemostasis situations.
Journal ArticleDOI
Potential applications of chitosan in veterinary medicine
Sevda Şenel,S.J. McClure +1 more
TL;DR: The veterinary drug delivery areas most likely to benefit from chitosan are the delivery of chemotherapeutics such as antibiotics, antiparasitics, anaesthetics, painkillers and growth promotants to mucosal epithelium for absorption for local or systemic activity, and the Delivery of immunomodulatory agents to the mucosal associated lymphoid tissue for induction or modulation of local immune responses.
Journal ArticleDOI
Photocrosslinkable chitosan as a biological adhesive.
Katsuaki Ono,Yoshio Saito,Hirohumi Yura,Keiichi Ishikawa,Akira Kurita,Toshihiro Akaike,Masayuki Ishihara +6 more
TL;DR: Results suggest that the photocrosslinkable chitosan developed here has the potential of serving as a new tissue adhesive in medical use.
References
More filters
Journal Article
The acceleration of wound healing with cartilage. I.
Prudden Jf,Nishihara G,Baker L +2 more
Journal ArticleDOI
The Acceleration of Wound Healing with Cartilage???I
J F Prudden,G Nishehara,L Baker +2 more
Journal ArticleDOI
The role of the granulocyte as a source of lysozyme in ulcerative colitis.
Journal ArticleDOI
The clinical acceleration of healing with a cartilage preparation; a controlled study.
John F. Prudden,John I. Allen +1 more
TL;DR: The overall percentage increase in tensile strength resulting from the treatment was 42%, and the difference is statistically highly significant, and the effectiveness of this material in the acceleration of human wound healing is considered established.
Journal ArticleDOI
Lysozyme content of granulation tissue.
TL;DR: It is now apparent that high lysozyme concentrations are associated with some mesodermal cell types as well as with epithelium, rendering less likely the possibility that granulation tissue is the source of the major fraction of the lyso enzyme titre in ulcerative alimentary disease.