Journal ArticleDOI
The effect of vitamin D on bone and osteoporosis.
Paul Lips,Natasja M. van Schoor +1 more
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TLDR
The main effect of the active vitamin D metabolite 1,25(OH)2D is to stimulate the absorption of calcium from the gut, which may decrease bone turnover and increase bone mineral density.About:
This article is published in Best Practice & Research Clinical Endocrinology & Metabolism.The article was published on 2011-08-01. It has received 382 citations till now. The article focuses on the topics: vitamin D deficiency & Osteomalacia.read more
Citations
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Journal ArticleDOI
The Nonskeletal Effects of Vitamin D: An Endocrine Society Scientific Statement
Clifford J. Rosen,John S. Adams,Daniel D. Bikle,Dennis M. Black,Marie B. Demay,JoAnn E. Manson,M. Hassan Murad,Christopher S. Kovacs +7 more
TL;DR: More studies are needed to definitively conclude that vitamin D can offer preventive and therapeutic benefits across a wide range of physiological states and chronic nonskeletal disorders.
Journal ArticleDOI
Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation
TL;DR: There remains some controversy regarding what blood level of 25-hydroxyvitamin D should be attained for both bone health and reducing risk for vitamin D deficiency associated acute and chronic diseases and how much vitamin DShould be supplemented.
Journal ArticleDOI
Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions.
Roger Bouillon,Claudio Marcocci,Geert Carmeliet,Daniel D. Bikle,John H. White,Bess Dawson-Hughes,Paul Lips,Craig F Munns,Craig F Munns,Marise Lazaretti-Castro,Andrea Giustina,John P. Bilezikian +11 more
TL;DR: There is a need for continued ongoing and future basic and clinical studies to better define whether vitamin D status can be optimized to improve many aspects of human health, and what is plausible regarding the health effects of vitamin D.
Journal ArticleDOI
Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis
TL;DR: Continuing widespread use of vitamin D for osteoporosis prevention in community-dwelling adults without specific risk factors for vitamin D deficiency seems to be inappropriate.
Journal ArticleDOI
Vitamin D Deficiency in India: Prevalence, Causalities and Interventions
Ritu G,Ajay Gupta +1 more
TL;DR: The status of vitamin D nutrition in the Indian subcontinent is reviewed and also the underlying causes for this epidemic are reviewed.
References
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Journal ArticleDOI
The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know
A. Catharine Ross,JoAnn E. Manson,Steven A. Abrams,John F. Aloia,John F. Aloia,Patsy M. Brannon,Steven K. Clinton,Ramon Durazo-Arvizu,J. Christopher Gallagher,Richard L. Gallo,Glenville Jones,Christopher S. Kovacs,Susan Taylor Mayne,Clifford J. Rosen,Sue A. Shapses +14 more
TL;DR: The Committee concluded that the prevalence of vitamin D inadequacy in North America has been overestimated and urgent research and clinical priorities were identified, including reassessment of laboratory ranges for 25-hydroxyvitamin D, to avoid problems of both undertreatment and overtreatment.
Journal ArticleDOI
Vitamin D3 and calcium to prevent hip fractures in elderly women
Marie Claire Chapuy,Monique E. Arlot,François Duboeuf,Jacqueline Brun,Bridgette Crouzet,Simone Arnaud,Pierre D. Delmas,Pierre J. Meunier +7 more
TL;DR: The effects of supplementation with vitamin D3 (cholecalciferol) and calcium on the frequency of hip fractures and other nonvertebral fractures, identified radiologically, in 3270 healthy ambulatory women are studied.
Journal ArticleDOI
Effect of Calcium and Vitamin D Supplementation on Bone Density in Men and Women 65 Years of Age or Older
TL;DR: In men and women 65 years of age or older who are living in the community, dietary supplementation with calcium and vitamin D moderately reduced bone loss measured in the femoral neck, spine, and total body over the three-year study period and reduced the incidence of nonvertebral fractures.
Journal ArticleDOI
Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications
TL;DR: Vitamin D3 is recommended in housebound elderly, and it may be cost-effective in hip fracture prevention in selected risk groups, and vitamin D3 supplementation may decrease the incidence of hip and other peripheral fractures in nursing home residents.
Journal ArticleDOI
Calcium plus vitamin D supplementation and the risk of fractures.
Rebecca D. Jackson,Andrea Z. LaCroix,Margery Gass,Robert B. Wallace,John A Robbins,Cora E. Lewis,Tamsen Bassford,Shirley A.A. Beresford,Henry R. Black,Patricia L. Blanchette,Denise E. Bonds,Robert L. Brunner,Robert G. Brzyski,Bette J. Caan,Jane A. Cauley,Rowan T. Chlebowski,Steven R. Cummings,Iris A. Granek,Jennifer Hays,Gerardo Heiss,Susan L. Hendrix,Barbara V. Howard,Judith Hsia,F. Allan Hubbell,Karen C. Johnson,Howard L. Judd,Jane Morley Kotchen,Lewis H. Kuller,Robert Langer,Norman L. Lasser,Marian C. Limacher,Shari E. Ludlam,JoAnn E. Manson,Karen L. Margolis,Joan McGowan,Judith K. Ockene,Mary Jo O'Sullivan,Lawrence S. Phillips,Ross L. Prentice,Gloria E. Sarto,Marcia L. Stefanick,Linda Van Horn,Jean Wactawski-Wende,Evelyn P Whitlock,Garnet L. Anderson,Annlouise R. Assaf,David H. Barad +46 more
TL;DR: Among healthy postmenopausal women, calcium with vitamin D supplementation resulted in a small but significant improvement in hip bone density, did not significantly reduce hip fracture, and increased the risk of kidney stones.