The global burden of tuberculosis mortality in children: a mathematical modelling study.
Peter J. Dodd,Courtney M. Yuen,Courtney M. Yuen,Charalambos Sismanidis,James A Seddon,Helen E. Jenkins +5 more
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TLDR
A global mortality burden estimate in children using a complementary approach not dependent on vital registration data is produced, implying substantial scope to reduce this burden.About:
This article is published in The Lancet Global Health.The article was published on 2017-09-01 and is currently open access. It has received 260 citations till now. The article focuses on the topics: Tuberculosis & Global health.read more
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Journal ArticleDOI
Building a tuberculosis-free world: The Lancet Commission on tuberculosis
Michael J. A. Reid,Nimalan Arinaminpathy,Amy Bloom,Barry R. Bloom,Catharina Boehme,Richard E. Chaisson,Daniel P. Chin,Gavin J. Churchyard,Helen Cox,Lucica Ditiu,Mark Dybul,Jeremy Farrar,Anthony S. Fauci,Endalkachew Fekadu,Paula I Fujiwara,Timothy B. Hallett,Christy L Hanson,Mark Harrington,Nick Herbert,Philip C. Hopewell,Chieko Ikeda,Dean T. Jamison,Aamir J. Khan,Irene Koek,Nalini Krishnan,Aaron Motsoaledi,Madhukar Pai,Mario C. Raviglione,Mario C. Raviglione,Almaz Sharman,Small Pm,Soumya Swaminathan,Zelalem Temesgen,Anna Vassall,Anna Vassall,Nandita. Venkatesan,Kitty van Weezenbeek,Gavin Yamey,Bruce D. Agins,Sofia Alexandru,Jason R. Andrews,Naomi Beyeler,Stela Bivol,Grania Brigden,Adithya Cattamanchi,Danielle Cazabon,Valeriu Crudu,Amrita Daftary,Puneet Dewan,Laurie K Doepel,Robert W Eisinger,Victoria Y. Fan,Victoria Y. Fan,Sara Fewer,Jennifer Furin,Jeremy D. Goldhaber-Fiebert,Gabriela B. Gomez,Stephen M. Graham,Stephen M. Graham,Stephen M. Graham,Devesh Gupta,Maureen Kamene,Sunil D. Khaparde,Eunice W Mailu,Enos Masini,Lorrie McHugh,Ellen M. H. Mitchell,Suerie Moon,Suerie Moon,Michael Osberg,Tripti Pande,Lea Prince,Kirankumar Rade,Raghuram Rao,Michelle Remme,James A Seddon,James A Seddon,Casey Selwyn,Priya B. Shete,Kuldeep Singh Sachdeva,Guy Stallworthy,Juan F. Vesga,Valentina Vilc,Eric Goosby +83 more
TL;DR: The Commission recommends five priority investments to achieve a tuberculosis-free world within a generation, which answer the question of how countries with high-burden tuberculosis and their development partners should target their future investments.
Journal ArticleDOI
Global, regional, and national burden of tuberculosis, 1990-2016: results from the Global Burden of Diseases, Injuries, and Risk Factors 2016 Study
Hmwe H Kyu,Emilie R Maddison,Nathaniel J Henry,Jorge R. Ledesma,Kirsten E. Wiens,Robert C. Reiner,Molly H Biehl,Chloe Shields,Aaron Osgood-Zimmerman,Jennifer M. Ross,Austin Carter,Tahvi Frank,Haidong Wang,Vinay Srinivasan,Sanjay K. Agarwal,Fares Alahdab,Kefyalew Addis Alene,Beriwan Abdulqadir Ali,Nelson Alvis-Guzman,Jason R. Andrews,Carl Abelardo T. Antonio,Suleman Atique,Sachin R Atre,Ashish Awasthi,Henok Tadesse Ayele,Hamid Badali,Alaa Badawi,Aleksandra Barac,Neeraj Bedi,Masoud Behzadifar,Meysam Behzadifar,Bayu Begashaw Bekele,Saba Abraham Belay,Isabela M. Benseñor,Zahid A Butt,Félix Carvalho,Kelly Cercy,Devasahayam J. Christopher,Alemneh Kabeta Daba,Lalit Dandona,Rakhi Dandona,Ahmad Daryani,Feleke Mekonnen Demeke,Kebede Deribe,Samath D Dharmaratne,David Teye Doku,Manisha Dubey,Dumessa Edessa,Ziad El-Khatib,Shymaa Enany,Eduarda Fernandes,Florian Fischer,Alberto L. García-Basteiro,Abadi Kahsu Gebre,Gebremedhin Berhe Gebregergs,Teklu Gebrehiwo Gebremichael,Tilayie Feto Gelano,Demeke Geremew,Philimon Gona,Amador Goodridge,Rashmi Gupta,Hassan Haghparast Bidgoli,Gessessew Bugssa Hailu,Hamid Yimam Hassen,Mohammad Taghi Hedayati,Andualem Henok,Sorin Hostiuc,Mamusha Aman Hussen,Olayinka Stephen Ilesanmi,Seyed Sina Naghibi Irvani,Kathryn H. Jacobsen,Sarah Charlotte Johnson,Jost B. Jonas,Amaha Kahsay,Surya Kant,Amir Kasaeian,Tesfaye Dessale Kassa,Yousef Khader,Morteza Abdullatif Khafaie,Ibrahim A Khalil,Ejaz Ahmad Khan,Young-Ho Khang,Yun Jin Kim,Sonali Kochhar,Ai Koyanagi,Kristopher J Krohn,G Anil Kumar,Ayenew Molla Lakew,Cheru Tesema Leshargie,Rakesh Lodha,Erlyn Rachelle King Macarayan,Reza Majdzadeh,Francisco Rogerlândio Martins-Melo,Addisu Melese,Ziad A. Memish,Walter Mendoza,Desalegn Tadese Mengistu,Getnet Mengistu,Tomislav Mestrovic,Babak Moazen,Karzan Abdulmuhsin Mohammad,Shafiu Mohammed,Ali H. Mokdad,Mahmood Moosazadeh,Seyyed Meysam Mousavi,Ghulam Mustafa,Jean B. Nachega,Long Hoang Nguyen,Son Hoang Nguyen,Trang Huyen Nguyen,Dina Nur Anggraini Ningrum,Yirga Legesse Nirayo,Vuong Minh Nong,Richard Ofori-Asenso,Felix Akpojene Ogbo,In-Hwan Oh,Olanrewaju Oladimeji,Andrew T Olagunju,Eyal Oren,David M. Pereira,Swayam Prakash,Mostafa Qorbani,Anwar Rafay,Rajesh Kumar Rai,Usha Ram,Salvatore Rubino,Saeid Safiri,Joshua A. Salomon,Abdallah M. Samy,Benn Sartorius,Maheswar Satpathy,Seyedmojtaba Seyedmousavi,Mehdi Sharif,João Pedro Silva,Dayane Gabriele Alves Silveira,Jasvinder A. Singh,Chandrashekhar T Sreeramareddy,Bach Xuan Tran,Afewerki Gebremeskel Tsadik,Kingsley N. Ukwaja,Irfan Ullah,Olalekan A. Uthman,Vasily Vlassov,Stein Emil Vollset,Giang Thu Vu,Fitsum Weldegebreal,Andrea Werdecker,Ebrahim M Yimer,Naohiro Yonemoto,Marcel Yotebieng,Mohsen Naghavi,Theo Vos,Simon I. Hay,Christopher J L Murray +153 more
TL;DR: If current trends in tuberculosis incidence continue, few countries are likely to meet the SDG target to end the tuberculosis epidemic by 2030, and several regions had higher rates of age-standardised incidence and mortality than expected on the basis of their SDI levels in 2016.
Journal ArticleDOI
Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children
TL;DR: In this paper , an open-label, treatment-shortening, non-inferiority trial involving children with nonsevere, symptomatic, presumably drug-susceptible, smear-negative tuberculosis in Uganda, Zambia, South Africa, and India was conducted, where children younger than 16 years of age were randomly assigned to 4 months (16 weeks) or 6 months (24 weeks) of standard first-line antituberculosis treatment with pediatric fixed-dose combinations.
Journal ArticleDOI
Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children
Alexander W. Kay,Lucia Gonzalez Fernandez,Yemisi Takwoingi,Michael Eisenhut,Anne Detjen,Karen R Steingart,Anna M. Mandalakas +6 more
TL;DR: A systematic review on the diagnostic accuracy of Xpert MTB/RIF or Xpert Ultra in children presumed to have active tuberculosis and rifampicin resistance in HIV‐positive and HIV‐negative children younger than 15 years was performed.
Journal ArticleDOI
The Wonder Years: What Can Primary School Children Teach Us About Immunity to Mycobacterium tuberculosis?
James A Seddon,James A Seddon,Silvia S. Chiang,Silvia S. Chiang,Hanif Esmail,Hanif Esmail,Anna K. Coussens +6 more
TL;DR: Understanding why primary school children, during what the authors term the “Wonder Years,” have low TB risk has implications for vaccine development, therapeutic interventions, and diagnostics and better understand the contribution of age and sex to M. tuberculosis immunity.
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