The hormone resistin links obesity to diabetes
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Cites background from "The hormone resistin links obesity ..."
...Adipocytes produce a variety of biologically active molecules (4–9), collectively known as adipocytokines or adipokines, including plasminogen activator inhibitor–1 (PAI-1) (10), TNF-α (11, 12), resistin (13, 14), leptin (15–17), and adiponectin (18–21)....
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Cites background from "The hormone resistin links obesity ..."
...Other potential mediators of insulin resistance deriving from adipose stores include tumor necrosis factor a,(49,50) leptin,(51,52) free fatty acids,(53) and resistin.(54) Nonetheless, under the assumption that elevated levels of IL-6 and CRP purely reflect altered adipocyte function, the ready availability of reliable and sensitive markers of this process may represent a novel approach for early identification of both obese and nonobese individuals at increased risk for the clinical development of this disease....
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