The impact of third generation genomic technologies on plant genome assembly.
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Cites background from "The impact of third generation geno..."
...However, despite recent technological improvements to simplify the generation of whole-genome de novo assemblies [8], there are so far only a few tools which use whole-genome assemblies as the basis for the identification of genomic differences [9]....
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Cites background from "The impact of third generation geno..."
...The sequencing technology combined with data analysis of genome has revolutionized our understanding of biology in the last two decades [2, 3] and—in many cases today—may allow us to predict the performance based on the genetic constitution of an organism [4]....
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"The impact of third generation geno..." refers methods in this paper
...Another elegant solution to the challenges of chromosome-scale assembly is based on chromosome conformation capture sequencing (Hi-C), a method originally developed to study the three-dimensional folding of the genome [54]....
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"The impact of third generation geno..." refers background in this paper
...Although raw reads can have sequencing error rates of up to 15%, correction with short sequencing reads [23,24] or selfcorrection with sufficient sequencing data [25] enables genome assemblies with a sequence accuracy of over 99....
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3,423 citations