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Journal ArticleDOI

The inferior parietal lobule and temporoparietal junction: A network perspective

01 Oct 2017-Neuropsychologia (Neuropsychologia)-Vol. 105, pp 70-83
TL;DR: This review aimed to synthesize findings from anatomical and functional studies of the IPL/TPJ that used neuroimaging at rest and during a wide range of tasks to discuss how network nodes within the IPJ are organized and how they participate in human perception and cognition.
About: This article is published in Neuropsychologia.The article was published on 2017-10-01. It has received 234 citations till now. The article focuses on the topics: Temporoparietal junction.
Citations
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Journal ArticleDOI
16 Feb 2018-eLife
TL;DR: It is found that the shape and exact location of brain regions interact strongly with the modelling of brain connectivity, and there is evidence that the spatial arrangement of functional regions is strongly predictive of non-imaging measures of behaviour and lifestyle.
Abstract: Brain connectivity is often considered in terms of the communication between functionally distinct brain regions. Many studies have investigated the extent to which patterns of coupling strength between multiple neural populations relates to behaviour. For example, studies have used 'functional connectivity fingerprints' to characterise individuals' brain activity. Here, we investigate the extent to which the exact spatial arrangement of cortical regions interacts with measures of brain connectivity. We find that the shape and exact location of brain regions interact strongly with the modelling of brain connectivity, and present evidence that the spatial arrangement of functional regions is strongly predictive of non-imaging measures of behaviour and lifestyle. We believe that, in many cases, cross-subject variations in the spatial configuration of functional brain regions are being interpreted as changes in functional connectivity. Therefore, a better understanding of these effects is important when interpreting the relationship between functional imaging data and cognitive traits.

192 citations

Journal ArticleDOI
01 Oct 2017-Cortex
TL;DR: The observed cross-talk demonstrates that SL of target selection and distractor filtering are instantiated via (at least partly) shared neuronal machinery, as further corroborated by strong correlations between direct and indirect effects at the level of individual participants.

131 citations

Journal ArticleDOI
07 Feb 2019-Cortex
TL;DR: It is proposed that the TPJ-pSTS is the basis of a third frontoparietal processing stream that underlies the increased social abilities in humans and is described as a hub that coordinates the activities of multiple brain networks in the exploration of the complex dynamic social scenes typical of the human social experience.

96 citations

Journal ArticleDOI
TL;DR: This study provides first evidence for distinct structural and functional correlates of behavioral addiction in individuals meeting psychometric criteria for SPA, and investigates gray matter volume and intrinsic neural activity in individuals with SPA.

90 citations

Journal ArticleDOI
TL;DR: There is a gradient organization in self-processing, through which body-environment information is integrated for the self via propagation from Interoceptive-processing to Mental-self-processing.

87 citations

References
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Journal ArticleDOI
TL;DR: Evidence for partially segregated networks of brain areas that carry out different attentional functions is reviewed, finding that one system is involved in preparing and applying goal-directed selection for stimuli and responses, and the other is specialized for the detection of behaviourally relevant stimuli.
Abstract: We review evidence for partially segregated networks of brain areas that carry out different attentional functions. One system, which includes parts of the intraparietal cortex and superior frontal cortex, is involved in preparing and applying goal-directed (top-down) selection for stimuli and responses. This system is also modulated by the detection of stimuli. The other system, which includes the temporoparietal cortex and inferior frontal cortex, and is largely lateralized to the right hemisphere, is not involved in top-down selection. Instead, this system is specialized for the detection of behaviourally relevant stimuli, particularly when they are salient or unexpected. This ventral frontoparietal network works as a 'circuit breaker' for the dorsal system, directing attention to salient events. Both attentional systems interact during normal vision, and both are disrupted in unilateral spatial neglect.

10,985 citations


"The inferior parietal lobule and te..." refers result in this paper

  • ...This pattern of activity may also be consistent with a role for the TPJa in bottom-up attentional reorienting, a function associated with the VAN (Corbetta and Shulman, 2002; Mitchell, 2008)....

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Journal ArticleDOI
TL;DR: A package of computer programs for analysis and visualization of three-dimensional human brain functional magnetic resonance imaging (FMRI) results is described and techniques for automatically generating transformed functional data sets from manually labeled anatomical data sets are described.

10,002 citations


"The inferior parietal lobule and te..." refers methods in this paper

  • ...The image volume was kindly shared by Buckner et al. (2009) and projected on the right hemisphere of the cvs_avg35_inMNI152 brain using AFNI/ SUMA software (Cox, 1996; Saad and Reynolds, 2012)....

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Journal ArticleDOI
TL;DR: This paper explores one aspect of cognition through the use of a simple model task in which human subjects are asked to commit attention to a position in visual space other than fixation by orienting a covert mechanism that seems sufficiently time locked to external events that its trajectory can be traced across the visual field in terms of momentary changes in the efficiency of detecting stimuli.
Abstract: Bartlett viewed thinking as a high level skill exhibiting ballistic properties that he called its “point of no return”. This paper explores one aspect of cognition through the use of a simple model...

9,130 citations


"The inferior parietal lobule and te..." refers background in this paper

  • ...Posner spatial-cueing tasks (Posner, 1980) have been instrumental in establishing the concept of a VAN....

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Journal ArticleDOI
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
Abstract: An MRI time course of 512 echo-planar images (EPI) in resting human brain obtained every 250 ms reveals fluctuations in signal intensity in each pixel that have a physiologic origin. Regions of the sensorimotor cortex that were activated secondary to hand movement were identified using functional MRI methodology (FMRI). Time courses of low frequency (< 0.1 Hz) fluctuations in resting brain were observed to have a high degree of temporal correlation (P < 10(-3)) within these regions and also with time courses in several other regions that can be associated with motor function. It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.

8,766 citations


"The inferior parietal lobule and te..." refers background in this paper

  • ...Voxels that are part of the same functional brain network show temporal synchrony of the low-frequency ( < 0.1 Hz) blood-oxygen-level dependent (BOLD) signal (Biswal, 2012; Biswal et al., 1995; Lowe, 2012)....

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Journal ArticleDOI
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
Abstract: Thirty years of brain imaging research has converged to define the brain’s default network—a novel and only recently appreciated brain system that participates in internal modes of cognition Here we synthesize past observations to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment Analysis of connectional anatomy in the monkey supports the presence of an interconnected brain system Providing insight into function, the default network is active when individuals are engaged in internally focused tasks including autobiographical memory retrieval, envisioning the future, and conceiving the perspectives of others Probing the functional anatomy of the network in detail reveals that it is best understood as multiple interacting subsystems The medial temporal lobe subsystem provides information from prior experiences in the form of memories and associations that are the building blocks of mental simulation The medial prefrontal subsystem facilitates the flexible use of this information during the construction of self-relevant mental simulations These two subsystems converge on important nodes of integration including the posterior cingulate cortex The implications of these functional and anatomical observations are discussed in relation to possible adaptive roles of the default network for using past experiences to plan for the future, navigate social interactions, and maximize the utility of moments when we are not otherwise engaged by the external world We conclude by discussing the relevance of the default network for understanding mental disorders including autism, schizophrenia, and Alzheimer’s disease

8,448 citations


"The inferior parietal lobule and te..." refers background or methods in this paper

  • ...The DMN was originally identified based on its consistent deactivation during tasks requiring focused attention, but it is now known to also be activated during broadly tuned attention to the environment as well as active internal cognition, such as mentalizing, autobiographical memory retrieval, or envisioning the future (Buckner et al., 2008)....

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  • ..., 2012b), which strongly overlaps with the network activated by theory-of-mind tasks (Buckner et al., 2008; Mars et al., 2012a) (red in Fig....

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  • ...…deactivation during tasks requiring focused attention, but it is now known to also be activated during broadly tuned attention to the environment as well as active internal cognition, such as mentalizing, autobiographical memory retrieval, or envisioning the future (Buckner et al., 2008)....

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  • ...The red network may correspond to the dMPFC subsystem, with clusters in the dorsal mPFC and temporal poles (a small IPL/TPJ node Data combined from Andrews-Hanna et al. (2010), Buckner et al. (2008, 2011), Corbetta et al. (2008), Dosenbach et al. (2007) and Vincent et al. (2008)....

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  • ...The IPL/TPJ is strongly associated with internally directed processes such as mind wandering and thinking about one's past or future (Buckner et al., 2008)....

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